PENTAZOCINE HYDROCHLORIDE

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Search structure


Trade Names	TALWIN 50
Synonyms	Pentazocine hcl Pentazocine hydrochloride Sosegon Talwin Talwin 50
Status
Molecule Category	Salt-form
UNII	A36BXO4PPX
Parent Compound:	PENTAZOCINE

Structure


InChI Key	OQGYMIIFOSJQSF-UHFFFAOYSA-N
Smiles	CC(C)=CCN1CCC2(C)c3cc(O)ccc3CC1C2C.Cl
InChI	InChI=1S/C19H27NO.ClH/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19;/h5-7,12,14,18,21H,8-11H2,1-4H3;1H

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C19H28ClNO
Molecular Weight	321.89
AlogP	3.88
Hydrogen Bond Acceptor	2.0
Hydrogen Bond Donor	1.0
Number of Rotational Bond	2.0
Polar Surface Area	23.47
Molecular species	BASE
Aromatic Rings	1.0
Heavy Atoms	21.0

Pharmacology

Mechanism of Action	Action	Reference
Sigma opioid receptor modulator	MODULATOR	PubMed DailyMed

Target Conservation


Protein: Sigma opioid receptor Description: Sigma non-opioid intracellular receptor 1 Organism : Homo sapiens Q99720 ENSG00000147955

Cross References

Resources	Reference
ChEMBL	CHEMBL3989510
FDA SRS	A36BXO4PPX
PubChem	441277
SureChEMBL	SCHEMBL40964

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025