EcoDrugPlus


Synonyms	Duranest [as hydrochloride] Etidocaine W-19053 W-19053 [AS HYDROCHLORIDE]
Status
Molecule Category	Free-form
ATC	N01BB07
UNII	K9D2CE52PU
EPA CompTox	DTXSID1023027


InChI Key	VTUSIVBDOCDNHS-UHFFFAOYSA-N
Smiles	CCCN(CC)C(CC)C(=O)Nc1c(C)cccc1C
InChI	InChI=1S/C17H28N2O/c1-6-12-19(8-3)15(7-2)17(20)18-16-13(4)10-9-11-14(16)5/h9-11,15H,6-8,12H2,1-5H3,(H,18,20)

Property Name	Value
Molecular Formula	C17H28N2O
Molecular Weight	276.42
AlogP	3.75
Hydrogen Bond Acceptor	2.0
Hydrogen Bond Donor	1.0
Number of Rotational Bond	7.0
Polar Surface Area	32.34
Molecular species	BASE
Aromatic Rings	1.0
Heavy Atoms	20.0

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Ion channel Voltage-gated ion channel Voltage-gated sodium channel	-	-	-	-	73.2

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Cavia porcellus	-	-	-	-	73.2

Resources	Reference
ChEBI	4904
ChEMBL	CHEMBL492
DrugBank	DB08987
DrugCentral	1097
FDA SRS	K9D2CE52PU
Guide to Pharmacology	2621
KEGG	C07530
PubChem	37497
SureChEMBL	SCHEMBL57261

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

ETIDOCAINE

Structure

Physicochemical Descriptors

Pharmacology

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