LEVAMISOLE

/static/temp/default.svg

Search structure


Synonyms	Levamisole TCMDC-125847 Tetramisole, (s)-
Status
Molecule Category	Free-form
ATC	P02CE01
UNII	2880D3468G
EPA CompTox	DTXSID4023206

Structure


InChI Key	HLFSDGLLUJUHTE-SNVBAGLBSA-N
Smiles	c1ccc([C@H]2CN3CCSC3=N2)cc1
InChI	InChI=1S/C11H12N2S/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10/h1-5,10H,6-8H2/t10-/m1/s1

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C11H12N2S
Molecular Weight	204.3
AlogP	2.15
Hydrogen Bond Acceptor	3.0
Number of Rotational Bond	1.0
Polar Surface Area	15.6
Molecular species	NEUTRAL
Aromatic Rings	1.0
Heavy Atoms	14.0

Pharmacology

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Enzyme	-	-	-	-	40

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Homo sapiens	-	-	-	-	40-70
Nippostrongylus brasiliensis	210	-	-	-	-
Rattus norvegicus	-	-	-	-	0-2

Environmental Exposure

Environmental Exposure Map

Countries
Croatia
Czech Republic
Hungary
Romania
Serbia
Slovenia

Cross References

Resources	Reference
ChEBI	6432
ChEMBL	CHEMBL1454
DrugBank	DB00848
DrugCentral	1561
FDA SRS	2880D3468G
Human Metabolome Database	HMDB0014986
Guide to Pharmacology	7210
KEGG	C07070
PharmGKB	PA450205
PubChem	26879
SureChEMBL	SCHEMBL19227
ZINC	ZINC000000119839

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025