EcoDrugPlus


Synonyms	C. i. mordant yellow 5 Dipentum Olsalazine
Status
Molecule Category	Free-form
ATC	A07EC03
UNII	ULS5I8J03O


InChI Key	QQBDLJCYGRGAKP-FOCLMDBBSA-N
Smiles	O=C(O)c1cc(/N=N/c2ccc(O)c(C(=O)O)c2)ccc1O
InChI	InChI=1S/C14H10N2O6/c17-11-3-1-7(5-9(11)13(19)20)15-16-8-2-4-12(18)10(6-8)14(21)22/h1-6,17-18H,(H,19,20)(H,21,22)/b16-15+

Property Name	Value
Molecular Formula	C14H10N2O6
Molecular Weight	302.24
AlogP	2.91
Hydrogen Bond Acceptor	6.0
Hydrogen Bond Donor	4.0
Number of Rotational Bond	4.0
Polar Surface Area	139.78
Molecular species	ACID
Aromatic Rings	2.0
Heavy Atoms	22.0

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Enzyme Oxidoreductase	-	-	70-70.79	-	-

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Homo sapiens	-	-	70-70.79	-	-

Resources	Reference
ChEMBL	CHEMBL425
DrugBank	DB01250
FDA SRS	ULS5I8J03O
Human Metabolome Database	HMDB0015380
KEGG	C07323
SureChEMBL	SCHEMBL25118
ZINC	ZINC000003812865

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

OLSALAZINE

Structure

Physicochemical Descriptors

Pharmacology

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