BEPRIDIL

/static/temp/default.svg Search structure
Synonyms
Status
Molecule Category Free-form
ATC C08EA02
UNII 755BO701MA
EPA CompTox DTXSID3022663

Structure

InChI Key UIEATEWHFDRYRU-UHFFFAOYSA-N
Smiles CC(C)COCC(CN(Cc1ccccc1)c1ccccc1)N1CCCC1
InChI
InChI=1S/C24H34N2O/c1-21(2)19-27-20-24(25-15-9-10-16-25)18-26(23-13-7-4-8-14-23)17-22-11-5-3-6-12-22/h3-8,11-14,21,24H,9-10,15-20H2,1-2H3

Physicochemical Descriptors

Property Name Value
Molecular Formula C24H34N2O
Molecular Weight 366.55
AlogP 4.83
Hydrogen Bond Acceptor 3.0
Number of Rotational Bond 10.0
Polar Surface Area 15.71
Molecular species BASE
Aromatic Rings 2.0
Heavy Atoms 27.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Ion channel Voltage-gated ion channel Potassium channels Voltage-gated potassium channel
- 22.91-550 - 184-444 -
Ion channel Voltage-gated ion channel Voltage-gated calcium channel
- 211-500 - - -
Ion channel Voltage-gated ion channel Voltage-gated sodium channel
- 840 - - 96.2
EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Canis lupus familiaris
- - - - 81
Cavia porcellus
- 211-840 - - 96.2
Homo sapiens
- 22.91-550 - 184-444 -

Cross References

Resources Reference
CAS NUMBER 64706-54-3
ChEBI 3061
ChEMBL CHEMBL1008
DrugBank DB01244
DrugCentral 342
FDA SRS 755BO701MA
Human Metabolome Database HMDB0015374
Guide to Pharmacology 2337
KEGG C06847
PharmGKB PA164754755
PubChem 2351
SureChEMBL SCHEMBL34412
CONTENTS