EcoDrugPlus


Trade Names	CEFIXIME SUPRAX
Synonyms	Anhydrous cefixime CL 284,635 CL-284635 Cefixime Cefixime anhydrous Cefixime hydrate Cefixime trihydrate Cefspan Cephoral Citropen FK 027 FK-027 FR 17027 FR-17027 Oroken
Status
Molecule Category	Free-form
ATC	J01DD08
UNII	XZ7BG04GJX


InChI Key	OKBVVJOGVLARMR-QSWIMTSFSA-N
Smiles	C=CC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)/C(=N\OCC(=O)O)c3csc(N)n3)[C@H]2SC1
InChI	InChI=1S/C16H15N5O7S2/c1-2-6-4-29-14-10(13(25)21(14)11(6)15(26)27)19-12(24)9(20-28-3-8(22)23)7-5-30-16(17)18-7/h2,5,10,14H,1,3-4H2,(H2,17,18)(H,19,24)(H,22,23)(H,26,27)/b20-9-/t10-,14-/m1/s1

Property Name	Value
Molecular Formula	C16H15N5O7S2
Molecular Weight	453.46
AlogP	-0.54
Hydrogen Bond Acceptor	10.0
Hydrogen Bond Donor	4.0
Number of Rotational Bond	8.0
Polar Surface Area	184.51
Molecular species	ACID
Aromatic Rings	1.0
Heavy Atoms	30.0

Mechanism of Action	Action	Reference
Bacterial penicillin-binding protein inhibitor	INHIBITOR	PubMed PubMed DailyMed Wikipedia Wikipedia

Resources	Reference
ChEBI	472657
ChEMBL	CHEMBL1541
DrugBank	DB00671
DrugCentral	537
FDA SRS	XZ7BG04GJX
Human Metabolome Database	HMDB0014809
Guide to Pharmacology	10898
KEGG	C06881
PDB	C04
PubChem	5491577
SureChEMBL	SCHEMBL24945
ZINC	ZINC000004468778

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

CEFIXIME

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Physicochemical Descriptors

Pharmacology

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