EcoDrugPlus


Trade Names	RENOQUID
Synonyms	CI-636 NSC-356717 Renoquid Sulfacitine Sulfacytine
Status
Molecule Category	Free-form
UNII	T795873AJP
EPA CompTox	DTXSID6023606

Trade Names

RENOQUID

Synonyms

CI-636

NSC-356717

Renoquid

Sulfacitine

Sulfacytine

Status

Molecule Category

Free-form

UNII

T795873AJP

EPA CompTox

DTXSID6023606


InChI Key	SIBQAECNSSQUOD-UHFFFAOYSA-N
Smiles	CCn1ccc(NS(=O)(=O)c2ccc(N)cc2)nc1=O
InChI	InChI=1S/C12H14N4O3S/c1-2-16-8-7-11(14-12(16)17)15-20(18,19)10-5-3-9(13)4-6-10/h3-8H,2,13H2,1H3,(H,14,15,17)

InChI Key

SIBQAECNSSQUOD-UHFFFAOYSA-N

Smiles

CCn1ccc(NS(=O)(=O)c2ccc(N)cc2)nc1=O

InChI

InChI=1S/C12H14N4O3S/c1-2-16-8-7-11(14-12(16)17)15-20(18,19)10-5-3-9(13)4-6-10/h3-8H,2,13H2,1H3,(H,14,15,17)

Property Name	Value
Molecular Formula	C12H14N4O3S
Molecular Weight	294.34
AlogP	0.65
Hydrogen Bond Acceptor	6.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	4.0
Polar Surface Area	107.08
Molecular species	NEUTRAL
Aromatic Rings	2.0
Heavy Atoms	20.0

Property Name

Value

Molecular Formula

C12H14N4O3S

Molecular Weight

294.34

AlogP

0.65

Hydrogen Bond Acceptor

6.0

Hydrogen Bond Donor

2.0

Number of Rotational Bond

4.0

Polar Surface Area

107.08

Molecular species

NEUTRAL

Aromatic Rings

2.0

Heavy Atoms

20.0

Mechanism of Action	Action	Reference
Dihydropteroate synthetase inhibitor	INHIBITOR	PubMed Wikipedia

Mechanism of Action

Action

Reference

Dihydropteroate synthetase inhibitor

INHIBITOR

PubMed Wikipedia

Resources	Reference
ChEBI	135230
ChEMBL	CHEMBL1201056
DrugBank	DB01298
DrugCentral	2499
FDA SRS	T795873AJP
Human Metabolome Database	HMDB0015412
PharmGKB	PA164754808
PubChem	5322
SureChEMBL	SCHEMBL49377
ZINC	ZINC000000002092

Resources

Reference

ChEBI

ChEMBL

DrugBank

DrugCentral

FDA SRS

Human Metabolome Database

PharmGKB

PubChem

SureChEMBL

ZINC

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

SULFACYTINE

Structure

Physicochemical Descriptors

Pharmacology

Cross References