Trade Names | |
Synonyms | |
Status | |
Molecule Category | Free-form |
UNII | 826Y60901U |
EPA CompTox | DTXSID2022672 |
Parent Compound: | BETAMETHASONE |
InChI Key | CIWBQSYVNNPZIQ-XYWKZLDCSA-N | |
---|---|---|
Smiles | ||
InChI |
|
Property Name | Value | |
---|---|---|
Molecular Formula | C28H37FO7 | |
Molecular Weight | 504.6 | |
AlogP | 3.82 | |
Hydrogen Bond Acceptor | 7.0 | |
Hydrogen Bond Donor | 1.0 | |
Number of Rotational Bond | 6.0 | |
Polar Surface Area | 106.97 | |
Molecular species | NEUTRAL | |
Aromatic Rings | 0.0 | |
Heavy Atoms | 36.0 |
Mechanism of Action | Action | Reference | |
---|---|---|---|
Glucocorticoid receptor agonist | AGONIST | PubMed DailyMed Wikipedia |
Protein: Glucocorticoid receptor Description: Glucocorticoid receptor Organism : Homo sapiens P04150 ENSG00000113580 |
||||
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | ||
---|---|---|---|---|---|---|---|
Transcription factor
Nuclear receptor
Nuclear hormone receptor subfamily 3
Nuclear hormone receptor subfamily 3 group C
Nuclear hormone receptor subfamily 3 group C member 1
|
- | 5 | - | - | - |
Resources | Reference | |
---|---|---|
ChEBI | 31276 | |
ChEMBL | CHEMBL1200384 | |
DrugCentral | 353 | |
FDA SRS | 826Y60901U | |
KEGG | D01637 | |
PubChem | 21800 | |
SureChEMBL | SCHEMBL7519 | |
ZINC | ZINC000004212137 |