Display Options:
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hematologic Neoplasms; Gaucher Disease
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Diagnostic agent
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Alzheimer Disease; Cognitive Dysfunction
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Phosphate sequestering agent
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Histone deacetylase inhibitor
ROUTE OF ADMINISTRATION: INTRAVENOUS
STATUS: Approved
THERAPEUTIC AREA: HEMATOLOGY
THERAPEUTIC INDICATION: Adenocarcinoma; Blast Crisis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Hematologic Neoplasms; Hodgkin Disease; Lymphoma; Lymphoma, Follicular; Mycosis Fungoides; Sarcoma; Small Cell Lung Carcinoma; Urinary Bladder Neoplasms; Burkitt Lymphoma; Carcinoma; Carcinoma, Endometrioid; Cystadenoma, Serous; Fallopian Tube Neoplasms; Glioblastoma; Leukemia, Myeloid, Acute; Leukemia-Lymphoma, Adult T-Cell; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous; Mesothelioma; Multiple Myeloma; Myelodysplastic Syndromes; Peritoneal Neoplasms; Thymoma; Lymphoma, T-Cell; Lymphoma, T-Cell, Peripheral; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hepatitis B, Chronic; Hepatitis C; Hepatitis C, Chronic; Virus Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Neuraminidase inhibitor
ROUTE OF ADMINISTRATION: INTRAVENOUS
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Influenza, Human; Influenza, Human; Virus Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Nonstructural protein 5A inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hepatitis B, Chronic; Lymphoma; Infections; Severe Acute Respiratory Syndrome; Hepatitis C; Hepatitis C, Chronic
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: ALK tyrosine kinase receptor inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: CANCER
THERAPEUTIC INDICATION: Liver Diseases; Cholangiocarcinoma; Glioblastoma; Granuloma, Plasma Cell; Lymphoma, Large-Cell, Anaplastic; Melanoma; Neuroblastoma; Thyroid Neoplasms; Sarcoma; Carcinoma, Non-Small-Cell Lung; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: CARDIOVASCULAR
THERAPEUTIC INDICATION: Crohn Disease; Hypertriglyceridemia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: PARP 1, 2 and 3 inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Central Nervous System Neoplasms; Cystadenocarcinoma, Serous; Glioma; Head and Neck Neoplasms; Hypertension, Pulmonary; Inflammatory Breast Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Neoplasm Metastasis; Neuroendocrine Tumors; Rhabdomyosarcoma; Uterine Neoplasms; Bile Duct Neoplasms; Biliary Tract Neoplasms; Carcinoma, Acinar Cell; Carcinoma, Ovarian Epithelial; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Carcinosarcoma; Cholangiocarcinoma; Colorectal Neoplasms; Glioblastoma; Hemangiosarcoma; Hereditary Breast and Ovarian Cancer Syndrome; Lung Neoplasms; Melanoma; Mesothelioma; Neoplasms, Germ Cell and Embryonal; Osteosarcoma; Pancreatic Neoplasms; Sarcoma; Sarcoma, Ewing; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Non-Small-Cell Lung; Endometrial Neoplasms; Fallopian Tube Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Stomach Neoplasms; Neoplasms; Ovarian Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Liver Diseases; Asthma; Pulmonary Disease, Chronic Obstructive; Lung Diseases, Obstructive
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Communicable Diseases; Urinary Tract Infections; Infections; Pneumonia; Pneumonia, Ventilator-Associated; Pyelonephritis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sodium/glucose cotransporter 2 inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: DIABETES DRUGS & ENDOCRINOLOGY; OTHER
THERAPEUTIC INDICATION: Acute Kidney Injury; Crohn Disease; Ascites; Colitis, Ulcerative; Familial Primary Pulmonary Hypertension; Glycogen Storage Disease Type I; Hypertension, Portal; Hypoglycemia; Hyponatremia; Inappropriate ADH Syndrome; Kidney Calculi; Kidney Diseases; Non-alcoholic Fatty Liver Disease; Polycystic Ovary Syndrome; Prediabetic State; Severe Acute Respiratory Syndrome; Cardiotoxicity; Diabetes Mellitus, Type 1; Diabetes, Gestational; Diabetic Nephropathies; Heart Failure; Insulin Resistance; Myocardial Infarction; Renal Insufficiency, Chronic; Diabetes Mellitus; Diabetes Mellitus, Type 2
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Nonstructural protein 5A inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hepatitis B, Chronic; Hepatitis C; Hepatitis C, Chronic
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Lanosterol 14-alpha demethylase inhibitor
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: DERMATOLOGY
THERAPEUTIC INDICATION: Onychomycosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Urticaria; Leishmaniasis; Leishmaniasis, Cutaneous; Leishmaniasis, Mucocutaneous; Leishmaniasis, Visceral; Trypanosomiasis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Hepatitis C virus serine protease, NS3/NS4A inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hepatitis B, Chronic; Hepatitis C; Hepatitis C, Chronic
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Adrenergic receptor agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
THERAPEUTIC INDICATION: Attention Deficit Disorder with Hyperactivity; Fibromyalgia; Hypotension; Parkinson Disease; Cardiovascular Diseases; Hypotension, Orthostatic; Multiple System Atrophy
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Alzheimer Disease; Cognitive Dysfunction
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Neurokinin 1 receptor antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Neoplasms; Postoperative Nausea and Vomiting
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Human immunodeficiency virus type 1 reverse transcriptase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Amyotrophic Lateral Sclerosis; Insulin Resistance; Hepatitis D; Leukemia, Lymphocytic, Chronic, B-Cell; Acquired Immunodeficiency Syndrome; HIV Infections; Hepatitis B, Chronic; Severe Acute Respiratory Syndrome; Virus Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Bacterial Infections; Renal Insufficiency; Systemic Inflammatory Response Syndrome; Urinary Tract Infections; Infections; Pneumonia; Pyelonephritis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: INTRAVENOUS
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Acute Coronary Syndrome; Coronary Disease; ST Elevation Myocardial Infarction; Ischemia; Thrombosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Solute carrier family 22 member 12 inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Gout; Hyperuricemia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 blocker
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Heart Failure, Diastolic; Heart Failure, Systolic; Hypotension; Lymphoma; Multiple Organ Failure; Non-ST Elevated Myocardial Infarction; Aging; Angina, Stable; Atrial Fibrillation; Coronary Disease; Diabetic Nephropathies; Heart Failure; Hypotension, Orthostatic; Mitral Valve Stenosis; Neoplasms; Shock, Septic; Tachycardia; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Neoplasms; Pulmonary Disease, Chronic Obstructive; Breast Neoplasms; Carcinoma, Squamous Cell; Cholangiocarcinoma; Colonic Neoplasms; Nasopharyngeal Neoplasms; Pancreatic Neoplasms; Rectal Neoplasms; Small Cell Lung Carcinoma; Urinary Bladder Neoplasms; Colorectal Neoplasms; Stomach Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cell membrane disrupting agent
ROUTE OF ADMINISTRATION: SUBCUTANEOUS
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Neurofibroma; Lipoma; Pain
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine D2 receptor partial agonist
ROUTE OF ADMINISTRATION: INTRAMUSCULAR
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Psychotic Disorders; Autistic Disorder; Bipolar Disorder; Depressive Disorder, Major; Schizophrenia; Tourette Syndrome
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine D2 receptor partial agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Alcoholism; Borderline Personality Disorder; Alzheimer Disease; Bipolar Disorder; Depressive Disorder; Psychomotor Agitation; Sleep Wake Disorders; Stress Disorders, Post-Traumatic; Depressive Disorder, Major; Psychotic Disorders; Schizophrenia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: INTRAVENOUS
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Leukemia, Lymphocytic, Chronic, B-Cell; Sarcoma, Ewing; Breast Neoplasms; Carcinoma, Ovarian Epithelial; Chondrosarcoma, Mesenchymal; Endocrine Gland Neoplasms; Fallopian Tube Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Liposarcoma, Myxoid; Meningioma; Mesothelioma; Pancreatic Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Soft Tissue Neoplasms; Ovarian Neoplasms; Sarcoma; Leiomyosarcoma; Liposarcoma; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: INHALATION
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Status Asthmaticus; Pulmonary Disease, Chronic Obstructive
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Human immunodeficiency virus type 1 reverse transcriptase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: HIV Infections; Hepatitis B, Chronic
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dual specificity mitogen-activated protein kinase kinase 1 inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Melanoma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Prostanoid IP receptor agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Familial Primary Pulmonary Hypertension; Pulmonary Arterial Hypertension; Thrombosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Prostatic Neoplasms; Sexual Dysfunctions, Psychological