TERBINAFINE HYDROCHLORIDE

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Search structure


Trade Names	LAMISIL LAMISIL AT TERBINAFINE HYDROCHLORIDE
Synonyms	Athlete's foot Bramazil Bramizil Lamisil Lamisil at Lamisil once Muzonal NSC-759113 Terbina Terbinafine (as hydrochloride) Terbinafine HCl Terbinafine hcl Terbinafine hydrochloride Terbine
Status
Molecule Category	Salt-form
UNII	012C11ZU6G
EPA CompTox	DTXSID90229223
Parent Compound:	TERBINAFINE

Structure


InChI Key	BWMISRWJRUSYEX-SZKNIZGXSA-N
Smiles	CN(C/C=C/C#CC(C)(C)C)Cc1cccc2ccccc12.Cl
InChI	InChI=1S/C21H25N.ClH/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19;/h5-7,9-14H,16-17H2,1-4H3;1H/b9-5+;

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C21H26ClN
Molecular Weight	327.9
AlogP	4.88
Hydrogen Bond Acceptor	1.0
Number of Rotational Bond	4.0
Polar Surface Area	3.24
Molecular species	BASE
Aromatic Rings	2.0
Heavy Atoms	22.0

Pharmacology

Mechanism of Action	Action	Reference
Squalene monooxygenase inhibitor	INHIBITOR	FDA

Cross References

Resources	Reference
ChEBI	77614
ChEMBL	CHEMBL1200832
FDA SRS	012C11ZU6G
KEGG	C08079
PubChem	5282481
SureChEMBL	SCHEMBL36793
ZINC	ZINC01530981

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025