EcoDrugPlus


Synonyms	ABBOTT-62254 Omnifiox Teflox Teflox 400 Temafloxacin hcl Temafloxacin hydrochloride
Status
Molecule Category	Salt-form
UNII	OC5IGJ7J6I

Synonyms

ABBOTT-62254

Omnifiox

Teflox

Teflox 400

Temafloxacin hcl

Temafloxacin hydrochloride

Status

Molecule Category

Salt-form

UNII

OC5IGJ7J6I


InChI Key	DDVJEYDLTXRYAJ-UHFFFAOYSA-N
Smiles	CC1CN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3-c2ccc(F)cc2F)CCN1.Cl
InChI	InChI=1S/C21H18F3N3O3.ClH/c1-11-9-26(5-4-25-11)19-8-18-13(7-16(19)24)20(28)14(21(29)30)10-27(18)17-3-2-12(22)6-15(17)23;/h2-3,6-8,10-11,25H,4-5,9H2,1H3,(H,29,30);1H

InChI Key

DDVJEYDLTXRYAJ-UHFFFAOYSA-N

Smiles

CC1CN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3-c2ccc(F)cc2F)CCN1.Cl

InChI

InChI=1S/C21H18F3N3O3.ClH/c1-11-9-26(5-4-25-11)19-8-18-13(7-16(19)24)20(28)14(21(29)30)10-27(18)17-3-2-12(22)6-15(17)23;/h2-3,6-8,10-11,25H,4-5,9H2,1H3,(H,29,30);1H

Property Name	Value
Molecular Formula	C21H19ClF3N3O3
Molecular Weight	453.85
AlogP	2.9
Hydrogen Bond Acceptor	5.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	3.0
Polar Surface Area	74.57
Molecular species	ZWITTERION
Aromatic Rings	3.0
Heavy Atoms	30.0

Property Name

Value

Molecular Formula

C21H19ClF3N3O3

Molecular Weight

453.85

AlogP

2.9

Hydrogen Bond Acceptor

5.0

Hydrogen Bond Donor

2.0

Number of Rotational Bond

3.0

Polar Surface Area

74.57

Molecular species

ZWITTERION

Aromatic Rings

3.0

Heavy Atoms

30.0

Mechanism of Action	Action	Reference
Bacterial DNA gyrase inhibitor	INHIBITOR	PubMed PubMed PubMed PubMed PubMed

Mechanism of Action

Action

Reference

Bacterial DNA gyrase inhibitor

INHIBITOR

PubMed PubMed PubMed PubMed PubMed

Resources	Reference
ChEMBL	CHEMBL2107495
FDA SRS	OC5IGJ7J6I
PubChem	60020
SureChEMBL	SCHEMBL134293

Resources

Reference

ChEMBL

FDA SRS

PubChem

SureChEMBL

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025

TEMAFLOXACIN HYDROCHLORIDE

Structure

Physicochemical Descriptors

Pharmacology

Cross References