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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial penicillin-binding protein inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Otitis Media
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Peroxisome proliferator-activated receptor alpha agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER
THERAPEUTIC INDICATION: Cholangitis, Sclerosing; Alcoholism; Burns; Diabetic Nephropathies; HIV Infections; Huntington Disease; Metabolic Syndrome; Multiple Myeloma; Non-alcoholic Fatty Liver Disease; Obesity; Atherosclerosis; Coronary Disease; Diabetic Retinopathy; Hyperlipidemia, Familial Combined; Hyperlipidemias; Hyperlipoproteinemia Type III; Hyperlipoproteinemias; Hypertension; Hypertriglyceridemia; Lipid Metabolism Disorders; Lipodystrophy; Liver Cirrhosis, Biliary; Metabolic Diseases; Cardiovascular Diseases; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dyslipidemias; Hypercholesterolemia; Hypothyroidism
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Mu opioid receptor agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Amphetamine-Related Disorders; Stress Disorders, Post-Traumatic; Substance-Related Disorders; Alzheimer Disease; Aortic Aneurysm, Abdominal; Breast Neoplasms; Neoplasms; Cardiomyopathy, Dilated; Diabetes Mellitus, Type 2; Hypertension; Marfan Syndrome; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Angiotensin-converting enzyme inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Essential Hypertension; Coronary Artery Disease; Hypertension
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Human herpesvirus 1 DNA polymerase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: IMMUNE SYSTEM; OTHER
THERAPEUTIC INDICATION: Multiple Sclerosis; Herpes Simplex; Meniere Disease; Autoimmune Diseases; Eye Infections; Herpes Genitalis; Herpes Labialis; Herpes Zoster; Virus Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Angiotensin-converting enzyme inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Human herpesvirus 1 DNA polymerase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: IMMUNE SYSTEM; OTHER
THERAPEUTIC INDICATION: HIV Infections; Herpes Simplex; Psychotic Disorders; Schizophrenia; Uveitis, Anterior; Cytomegalovirus Infections; Chickenpox; Herpes Genitalis; Herpes Labialis; Herpes Zoster
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: CARDIOVASCULAR; IMMUNE SYSTEM; OTHER
THERAPEUTIC INDICATION: Arthritis, Rheumatoid; Carcinoma, Renal Cell; DiGeorge Syndrome; Glioblastoma; Gliosarcoma; Hypertension; Lecithin Cholesterol Acyltransferase Deficiency; Lymphoma, T-Cell; Pancreatic Neoplasms; Scleroderma, Diffuse; Small Cell Lung Carcinoma; beta-Thalassemia; Amyotrophic Lateral Sclerosis; Anemia, Aplastic; Anemia, Diamond-Blackfan; Anemia, Sickle Cell; Autoimmune Diseases; Burkitt Lymphoma; Chemical and Drug Induced Liver Injury; Crohn Disease; Epidermolysis Bullosa; Fanconi Anemia; Gout; Granuloma, Lethal Midline; HIV Infections; Hematologic Diseases; Hematologic Neoplasms; Hepatitis, Alcoholic; Histiocytosis, Langerhans-Cell; Hyperlipoproteinemia Type I; IgA Vasculitis; Immunoblastic Lymphadenopathy; Immunologic Deficiency Syndromes; Kidney Neoplasms; Leukemia, Hairy Cell; Leukemia, Large Granular Lymphocytic; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Mast-Cell; Leukemia, Myelomonocytic, Chronic; Leukemia, Myelomonocytic, Juvenile; Leukemia, Prolymphocytic, B-Cell; Leukemia, Prolymphocytic, T-Cell; Leukemia-Lymphoma, Adult T-Cell; Liver Diseases; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell, Peripheral; Macular Degeneration; Melanoma; Multiple Sclerosis; Mycosis Fungoides; Myeloproliferative Disorders; Neuroblastoma; Neuronal Ceroid-Lipofuscinoses; Pemphigoid, Benign Mucous Membrane; Pemphigoid, Bullous; Polycythemia Vera; Primary Myelofibrosis; Psoriasis; Scleroderma, Limited; Scleroderma, Systemic; Severe Combined Immunodeficiency; Sezary Syndrome; Shwachman-Diamond Syndrome; Sjogren's Syndrome; Vasculitis; Wiskott-Aldrich Syndrome; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Carcinoma, Hepatocellular; Cardiovascular Diseases; Cystitis, Interstitial; Cytomegalovirus Infections; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Glomerulonephritis, IGA; Glomerulonephritis, Membranous; Glomerulosclerosis, Focal Segmental; Graft vs Host Disease; Granulomatosis with Polyangiitis; Heart Diseases; Hepatitis C; Hodgkin Disease; Kidney Diseases; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Lung Diseases, Interstitial; Lupus Erythematosus, Systemic; Lupus Nephritis; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Microscopic Polyangiitis; Multiple Myeloma; Myasthenia Gravis; Myelodysplastic Syndromes; Neoplasms; Nephrotic Syndrome; Neuromyelitis Optica; Pemphigus; Polyradiculopathy; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purpura, Thrombocytopenic, Idiopathic; Red-Cell Aplasia, Pure; Renal Insufficiency; Renal Insufficiency, Chronic; Sarcoidosis, Pulmonary; Takayasu Arteritis; Uveitis; Waldenstrom Macroglobulinemia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial 70S ribosome inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: DERMATOLOGY
THERAPEUTIC INDICATION: Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Ependymoma; Glioma; Infectious Mononucleosis; Lung Neoplasms; Prostatic Neoplasms; Astrocytoma; Bipolar Disorder; Cytomegalovirus Infections; Glioblastoma; Hepatitis C, Chronic; Leukemia, Lymphocytic, Chronic, B-Cell; Neuralgia, Postherpetic; Psychotic Disorders; Pulmonary Disease, Chronic Obstructive; Schizophrenia; Stomatitis, Herpetic; Waldenstrom Macroglobulinemia; Encephalitis; Herpes Simplex; Neoplasms; Pregnancy; Prostatic Neoplasms, Castration-Resistant; Herpes Genitalis; Herpes Labialis; Herpes Zoster; Virus Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Reactive metabolite scavenging agent
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: DIABETES DRUGS & ENDOCRINOLOGY; OTHER
THERAPEUTIC INDICATION: Chordoma; Fanconi Anemia; Kidney Neoplasms; Leukemia, Myeloid, Acute; Liver Neoplasms; Mesothelioma; Myeloproliferative Disorders; Neoplasms; Neoplasms, Germ Cell and Embryonal; Neuroblastoma; Retinoblastoma; Brain Neoplasms; Breast Neoplasms; Central Nervous System Neoplasms; Colorectal Neoplasms; Endometrial Neoplasms; Fallopian Tube Neoplasms; Hodgkin Disease; Leukemia; Lymphoma; Lymphoma, Non-Hodgkin; Myelodysplastic Syndromes; Peritoneal Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Sarcoma; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Squamous Cell; Hepatoblastoma; Lung Neoplasms; Multiple Myeloma; Peripheral Nervous System Diseases; Trigeminal Neuralgia; Head and Neck Neoplasms; Ovarian Neoplasms; Xerostomia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Liver Cirrhosis, Biliary; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Adrenergic receptor alpha-1 agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: CARDIOVASCULAR; OTHER
THERAPEUTIC INDICATION: Hypotension, Orthostatic; Sepsis; Stroke; Shock, Septic
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hepatopulmonary Syndrome; Hypotension, Orthostatic; Ischemic Stroke; Ascites; Hypotension; Shock, Septic; Spinal Cord Injuries; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA polymerase (alpha/delta/epsilon) inhibitor
ROUTE OF ADMINISTRATION: INJECTION; INTRAVENOUS
STATUS: Approved
THERAPEUTIC AREA: CANCER; OTHER; UROLOGY AND KIDNEY
THERAPEUTIC INDICATION: Carcinoma, Renal Cell; Endometrial Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Klatskin Tumor; Lymphoma, Follicular; Lymphoma, T-Cell; Lymphoproliferative Disorders; Mycosis Fungoides; Stomach Neoplasms; Uterine Neoplasms; Breast Neoplasms, Male; Carcinoma; Carcinoma, Endometrioid; Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Cystadenoma, Serous; Fallopian Tube Neoplasms; Head and Neck Neoplasms; Hodgkin Disease; Kidney Neoplasms; Leukemia; Leukemia, Plasma Cell; Liver Neoplasms; Lymphoma, Mantle-Cell; Mesothelioma; Multiple Myeloma; Nasopharyngeal Neoplasms; Peritoneal Neoplasms; Plasmacytoma; Prostatic Neoplasms, Castration-Resistant; Retroviridae Infections; Sarcoma; Ureteral Neoplasms; Cholangiocarcinoma; Gallbladder Neoplasms; Lung Neoplasms; Lymphoma; Neoplasms; Thromboembolism; Triple Negative Breast Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Ovarian Neoplasms; Pancreatic Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sodium channel alpha subunit blocker
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Seizures
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Prostanoid FP receptor agonist
ROUTE OF ADMINISTRATION: OPHTHALMIC
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Meniere Disease; Vitiligo; Glaucoma; Glaucoma, Open-Angle; Hypertension; Ocular Hypertension
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Astrocytoma; Bone Neoplasms; Carcinoid Tumor; Diffuse Intrinsic Pontine Glioma; Digestive System Neoplasms; Endometrial Neoplasms; Kidney Neoplasms; Liver Neoplasms; Mesothelioma; Oligodendroglioma; Pulmonary Disease, Chronic Obstructive; Biliary Tract Neoplasms; Carcinoma; Carcinoma, Islet Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Fallopian Tube Neoplasms; Ganglioneuroblastoma; Glioblastoma; Glioma; Gliosarcoma; Head and Neck Neoplasms; Hemangiosarcoma; Leukemia; Lymphoma; Lymphoma, Non-Hodgkin; Medulloblastoma; Neuroblastoma; Ovarian Neoplasms; Peritoneal Neoplasms; Pinealoma; Rhabdomyosarcoma; Sarcoma; Triple Negative Breast Neoplasms; Wilms Tumor; Adenocarcinoma, Mucinous; Brain Neoplasms; Breast Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Neuroendocrine; Carcinoma, Pancreatic Ductal; Cholangiocarcinoma; Choroid Plexus Neoplasms; Colonic Neoplasms; Colorectal Neoplasms; Esophageal Neoplasms; Hepatoblastoma; Lung Neoplasms; Neoplasm Metastasis; Pancreatic Neoplasms; Rectal Neoplasms; Sarcoma, Ewing; Small Cell Lung Carcinoma; Stomach Neoplasms; Uterine Cervical Neoplasms; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Status Epilepticus; Epilepsy
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Angiotensin-converting enzyme inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: DIABETES DRUGS & ENDOCRINOLOGY; OTHER
THERAPEUTIC INDICATION: Cardiovascular Diseases; Heart Failure; Hypertension; Myocardial Infarction; Ventricular Dysfunction, Left
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA topoisomerase I inhibitor
ROUTE OF ADMINISTRATION: INJECTION; INTRAVENOUS
STATUS: Approved
THERAPEUTIC AREA: CANCER; OTHER
THERAPEUTIC INDICATION: Anus Neoplasms; Appendiceal Neoplasms; Burkitt Lymphoma; Carcinoid Tumor; Carcinoma, Basal Cell; Carcinoma, Ovarian Epithelial; Carcinoma, Renal Cell; Carcinoma, Verrucous; Endometrial Neoplasms; Esthesioneuroblastoma, Olfactory; Gastrointestinal Stromal Tumors; Granuloma, Lethal Midline; Hodgkin Disease; Hypopharyngeal Neoplasms; Immunoblastic Lymphadenopathy; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia-Lymphoma, Adult T-Cell; Lymphoma, AIDS-Related; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Melanoma; Mycosis Fungoides; Neoplasms; Neutropenia; Oropharyngeal Neoplasms; Papilloma, Inverted; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms, Castration-Resistant; Salivary Gland Neoplasms; Sarcoma, Ewing; Sezary Syndrome; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms; Uterine Cervical Neoplasms; Astrocytoma; Biliary Tract Neoplasms; Breast Neoplasms; Carcinoma, Merkel Cell; Carcinoma, Neuroendocrine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Choroid Plexus Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Ganglioneuroblastoma; Glioblastoma; Glioma; Gliosarcoma; Head and Neck Neoplasms; Kidney Neoplasms; Liver Neoplasms; Lymphoma; Medulloblastoma; Meningioma; Neuroblastoma; Neuroectodermal Tumors, Primitive, Peripheral; Oligodendroglioma; Osteosarcoma; Ovarian Neoplasms; Penile Neoplasms; Peritoneal Neoplasms; Pinealoma; Rhabdomyosarcoma; Small Cell Lung Carcinoma; Urethral Neoplasms; Urinary Bladder Neoplasms; Carcinoma, Pancreatic Ductal; Colonic Neoplasms; Colorectal Neoplasms; Diarrhea; Hepatoblastoma; Lung Neoplasms; Mesenchymoma; Pancreatic Neoplasms; Rectal Neoplasms; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Sarcoma; Stomach Neoplasms; Adenocarcinoma; Carcinoma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Bile Duct Neoplasms; Brain Neoplasms; Leukemia; Leukemia, Myeloid, Acute; Lymphoma, T-Cell, Cutaneous; Sarcoma, Synovial; Stomach Neoplasms; Adenocarcinoma; Adenocarcinoma of Lung; Anxiety; Biliary Tract Diseases; Carcinoma, Large Cell; Carcinoma, Ovarian Epithelial; Carcinoma, Renal Cell; Colonic Neoplasms; Colorectal Neoplasms; Digestive System Diseases; Endometrial Neoplasms; Esophageal Neoplasms; Gastrointestinal Stromal Tumors; Head and Neck Neoplasms; Hodgkin Disease; Kidney Neoplasms; Leiomyosarcoma; Leukemia-Lymphoma, Adult T-Cell; Liver Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, T-Cell; Medulloblastoma; Melanoma; Multiple Myeloma; Neoplasms, Germ Cell and Embryonal; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Sarcoma, Ewing; Small Cell Lung Carcinoma; Testicular Neoplasms; Thyroid Neoplasms; Urethral Neoplasms; Biliary Tract Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cholangiocarcinoma; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Granuloma, Lethal Midline; Hepatoblastoma; Immunoblastic Lymphadenopathy; Lung Neoplasms; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Mesothelioma; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Sarcoma; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA topoisomerase II alpha inhibitor
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Fallopian Tube Neoplasms; Leukemia, Myeloid, Acute; Multiple Myeloma; Oligodendroglioma; Ovarian Neoplasms; Peritoneal Neoplasms; Glioma; Leukemia; Leukemia, Biphenotypic, Acute; Lymphoma; Lymphoma, Non-Hodgkin; Medulloblastoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Rhabdomyosarcoma; Carcinoma; Central Nervous System Neoplasms; Hodgkin Disease; Lymphoma, Follicular; Neuroblastoma; Carcinoma, Small Cell; Lung Neoplasms; Neoplasms; Small Cell Lung Carcinoma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Estrogen receptor modulator
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Fractures, Bone; Osteoporosis; Breast Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Cardiovascular Diseases; Depressive Disorder, Major; Diabetes Mellitus, Type 2; Head and Neck Neoplasms; Lupus Erythematosus, Systemic; Asthma; HIV Infections; Heart Diseases; Hypertension, Pulmonary; Intermittent Claudication; Peripheral Vascular Diseases; Pneumonia, Viral; Polycythemia Vera; Pregnancy; Respiratory Insufficiency; Scleroderma, Systemic; Venous Thromboembolism; Acute Coronary Syndrome; Angina, Stable; Aortic Valve Stenosis; Arteriosclerosis; Atherosclerosis; Atrial Fibrillation; Brain Infarction; Carotid Stenosis; Coronary Disease; Gastrointestinal Hemorrhage; Heart Defects, Congenital; Heart Failure; Hemorrhage; Influenza, Human; Intracranial Aneurysm; Intracranial Arteriosclerosis; Ischemia; Ischemic Attack, Transient; Ischemic Stroke; Myocardial Infarction; Peripheral Arterial Disease; Pneumonia; Renal Insufficiency, Chronic; ST Elevation Myocardial Infarction; Severe Acute Respiratory Syndrome; Stroke; Thrombophilia; Vascular Diseases; Thrombosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glucocorticoid receptor agonist
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Adrenal Hyperplasia, Congenital; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Bursitis; Colitis, Ulcerative; Conjunctivitis, Allergic; Dermatitis; Dermatitis, Atopic; Dermatitis, Seborrheic; Endocrine System Diseases; Exanthema; Inflammation; Leukemia; Lymphoma; Neoplasms; Osteoarthritis; Pruritus; Psoriasis; Serum Sickness; Skin Diseases; Spondylitis; Tenosynovitis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Purinergic receptor P2Y12 antagonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER
THERAPEUTIC INDICATION: Coronary Disease; Breast Neoplasms; Gastrointestinal Hemorrhage; Acute Coronary Syndrome; Angina, Unstable; Ischemia; Myocardial Infarction; Peripheral Arterial Disease; Stroke
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial DNA gyrase inhibitor
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Fibromatosis, Aggressive; Ovarian Neoplasms; Prostatic Neoplasms, Castration-Resistant; Severe Acute Respiratory Syndrome; Breast Neoplasms; Fractures, Bone; Mastodynia; Prostatic Intraepithelial Neoplasia; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: CARDIOVASCULAR; OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glucocorticoid receptor agonist
ROUTE OF ADMINISTRATION: OPHTHALMIC
STATUS: Approved
THERAPEUTIC AREA: EYE; OTHER
THERAPEUTIC INDICATION: Eye Pain; Blepharitis; Cataract; Conjunctivitis, Allergic; Dry Eye Syndromes; Eye Diseases; Inflammation; Uveitis, Anterior
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dihydroorotate dehydrogenase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: DIABETES DRUGS & ENDOCRINOLOGY; OTHER; RHEUMATOLOGY
THERAPEUTIC INDICATION: Breast Neoplasms; HIV Infections; Melanoma; Neoplasms; IgA Vasculitis; Lupus Erythematosus, Systemic; Lymphoproliferative Disorders; Multiple Myeloma; Pemphigoid, Bullous; Prostatic Neoplasms, Castration-Resistant; Sjogren's Syndrome; Smoldering Multiple Myeloma; Uveitis; Arthritis, Psoriatic; Central Nervous System Neoplasms; Lupus Nephritis; Myasthenia Gravis; Polymyalgia Rheumatica; Severe Acute Respiratory Syndrome; Arthritis, Rheumatoid; Immune System Diseases; Multiple Sclerosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Type-1 angiotensin II receptor antagonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER
THERAPEUTIC INDICATION: Pain; Severe Acute Respiratory Syndrome; Atherosclerosis; Breast Neoplasms; Coronary Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Essential Hypertension; Hypercholesterolemia; Hypertension, Renovascular; Proteinuria; Renal Artery Obstruction; Angina Pectoris; Cardiovascular Diseases; Diabetes Mellitus; Heart Failure; Hypertension; Myocardial Infarction; Stroke
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Human immunodeficiency virus type 1 reverse transcriptase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Psoriasis; AIDS Dementia Complex; Autoimmune Diseases; HIV Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hepatitis C; Acidosis, Lactic; Lipodystrophy; Sarcoma, Kaposi; Acquired Immunodeficiency Syndrome; Amyotrophic Lateral Sclerosis; HIV Infections; Tuberculosis; Virus Diseases