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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Carcinoma, Hepatocellular; Glioblastoma; Hematologic Neoplasms; Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Pancreatic Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial penicillin-binding protein inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Tuberculosis; Tuberculosis, Pulmonary; Bacterial Infections; Pneumonia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Platelet-derived growth factor receptor inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Breast Neoplasms; Carcinoid Tumor; Carcinoma, Renal Cell; Cholangiocarcinoma; Esophageal Neoplasms; Lung Neoplasms; Melanoma; Nasopharyngeal Neoplasms; Neoplasms; Pancreatic Neoplasms; Triple Negative Breast Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Gastrointestinal Stromal Tumors
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cyclooxygenase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Liver Diseases; Renal Insufficiency; Osteoarthritis; Osteoarthritis, Hip; Rheumatic Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Hepatitis C virus serine protease, NS3/NS4A inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: HIV Infections; Renal Insufficiency; Hepatitis C; Hepatitis C, Chronic; Virus Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Autistic Disorder; Low Back Pain; Marijuana Abuse; Psychotic Disorders; Schizophrenia; Stress Disorders, Post-Traumatic; Substance Withdrawal Syndrome; Wounds and Injuries
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA polymerase/reverse transcriptase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hepatitis C, Chronic; Insulin Resistance; Acquired Immunodeficiency Syndrome; Carcinoma, Hepatocellular; HIV Infections; Hepatitis B, Chronic; Hepatitis D; Infections; Severe Acute Respiratory Syndrome
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cholesteryl ester transfer protein inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Coronary Disease; Hypercholesterolemia; Hyperlipidemia, Familial Combined; Hyperlipidemias; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type III; Hyperlipoproteinemia Type IV; Hypertriglyceridemia; Lipid Metabolism Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: TEC family kinase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Kidney Diseases; Liver Diseases; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Vitiligo; Alopecia Areata
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Peroxisome proliferator-activated receptor alpha agonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Diabetes Mellitus, Type 2
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Breast Neoplasms; Neoplasm Metastasis; Colorectal Neoplasms; Lung Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Carcinoma, Non-Small-Cell Lung
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Biliary Tract Neoplasms; Colorectal Neoplasms; Sarcoma; Carcinoma, Pancreatic Ductal; Leukemia; Lymphoma; Lymphoma, Non-Hodgkin; Myelodysplastic Syndromes; Neoplasms; Leukemia, Myeloid, Acute; Pancreatic Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dipeptidyl peptidase IV inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Kidney Diseases; Liver Diseases; Aortic Valve Disease; Diabetes Mellitus; Diabetes Mellitus, Type 2
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Beta-secretase 1 inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Alzheimer Disease
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Bipolar Disorder
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Gingivitis; Osteoporosis, Postmenopausal; Dental Caries
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Helicase primate complex inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Herpes Genitalis; Herpes Simplex; Herpes Zoster; Virus Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Tyrosine-protein kinase BTK inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Kidney Diseases; Arthritis, Rheumatoid; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Endothelin receptor, ET-A/ET-B antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Kidney Diseases; Liver Diseases; Essential Hypertension; Hypertension
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Hepatitis C virus serine protease, NS3/NS4A inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Liver Diseases; Hepatitis C, Chronic; Hepatitis C
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Vanilloid receptor antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cholesteryl ester transfer protein inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Lipid Metabolism Disorders; Cardiovascular Diseases; Hypercholesterolemia; Hyperlipidemias
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Atrial Fibrillation; Tachycardia, Ventricular
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sphingosine 1-phosphate receptor Edg-1 agonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Alopecia Areata; Crohn Disease; Dermatitis, Atopic; Eosinophilic Esophagitis; Inflammatory Bowel Diseases; Liver Cirrhosis, Biliary; Pyoderma; Colitis, Ulcerative
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dipeptidyl peptidase IV inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Diabetes Mellitus; Diabetes Mellitus, Type 2
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Receptor protein-tyrosine kinase erbB-2 inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Vitamin D receptor agonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Osteoporosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: MAP kinase p38 alpha inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Cardiovascular Diseases; Arthritis, Rheumatoid; Atherosclerosis; Depressive Disorder, Major; Glomerulosclerosis, Focal Segmental; Lipid Metabolism Disorders; Neuralgia; Pulmonary Disease, Chronic Obstructive; Acute Coronary Syndrome; Muscular Dystrophy, Facioscapulohumeral; Severe Acute Respiratory Syndrome
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Ribonucleotide reductase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Carcinoid Tumor; Neoplasms; Breast Neoplasms, Male; Carcinoma, Non-Small-Cell Lung; Gallbladder Neoplasms; Kidney Neoplasms; Lung Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Ovarian Neoplasms; Colorectal Neoplasms; Melanoma; Leukemia, Myeloid, Acute
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA polymerase/reverse transcriptase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: HIV Infections; Hepatitis B, Chronic
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Neurokinin 1 receptor antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Depressive Disorder, Major; Dyspepsia; Sleep Initiation and Maintenance Disorders; Urinary Bladder, Overactive; Nausea; Postoperative Nausea and Vomiting; Vomiting