MP-412

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Synonyms
Status
Molecule Category Mixture
UNII Z541VW0W40

Structure

InChI Key JZDDKMMYGMSSFH-UHFFFAOYSA-N
Smiles C=CC(=O)Nc1cc(C#CC(C)(C)N2CCN(C)CC2)cc2ncnc(Nc3ccc(F)c(Cl)c3)c12
InChI
InChI=1S/C27H28ClFN6O/c1-5-24(36)33-23-15-18(8-9-27(2,3)35-12-10-34(4)11-13-35)14-22-25(23)26(31-17-30-22)32-19-6-7-21(29)20(28)16-19/h5-7,14-17H,1,10-13H2,2-4H3,(H,33,36)(H,30,31,32)

Pharmacology

Mechanism of Action Action Reference
Epidermal growth factor receptor erbB1 inhibitor INHIBITOR PubMed PubMed

Target Conservation

Protein: Epidermal growth factor receptor erbB1
Description: Epidermal growth factor receptor
Organism : Homo sapiens
P00533 ENSG00000146648
Protein: Receptor protein-tyrosine kinase erbB-2
Description: Receptor tyrosine-protein kinase erbB-2
Organism : Homo sapiens
P04626 ENSG00000141736

Cross References

Resources Reference
ChEMBL CHEMBL3545002
FDA SRS Z541VW0W40
CONTENTS