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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial 70S ribosome inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA topoisomerase II alpha inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Multiple Myeloma; Breast Neoplasms; Sarcoma; Thymoma; Urinary Bladder Neoplasms; Lung Neoplasms; Neoplasms; Small Cell Lung Carcinoma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: HIV Infections; Melanoma; Amyotrophic Lateral Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Multiple System Atrophy; Myocardial Infarction; Diabetic Neuropathies; Eye Diseases; Jaundice, Obstructive; Parkinson Disease; Virus Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Osteoporosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Leukemia; Neoplasms; Myelodysplastic Syndromes; Myeloproliferative Disorders; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Leukemia, Myeloid, Acute
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Selectin E antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Severe Acute Respiratory Syndrome; Venous Thrombosis; Multiple Myeloma; Leukemia, Myeloid, Acute
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hemorrhage; Severe Acute Respiratory Syndrome
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Esophageal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Breast Neoplasms; Colorectal Neoplasms; Head and Neck Neoplasms; Rectal Neoplasms; Stomach Neoplasms; Urinary Bladder Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hypertension; Pre-Eclampsia; Stroke
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine receptors; D2 & D3 partial agonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Parkinson Disease
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Bipolar Disorder; Lung Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Acquired Immunodeficiency Syndrome; Neuroblastoma; Uterine Cervical Neoplasms; Carcinoma, Adenoid Cystic; Carcinoma, Neuroendocrine; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Esophageal Neoplasms; Granuloma, Lethal Midline; HIV Infections; Hodgkin Disease; Immunoblastic Lymphadenopathy; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Lymphoma, Follicular; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous; Multiple Myeloma; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma; Thrombocytopenia; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Breast Neoplasms; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, T-Cell, Peripheral
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dihydropyrimidine dehydrogenase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Kidney Diseases; Liver Diseases; Uterine Cervical Neoplasms; Biliary Tract Neoplasms; Breast Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Neuroendocrine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Nasopharyngeal Neoplasms; Neoplasms; Rectal Neoplasms; Small Cell Lung Carcinoma; Adenocarcinoma; Cholangiocarcinoma; Colorectal Neoplasms; Esophageal Neoplasms; Head and Neck Neoplasms; Pancreatic Neoplasms; Stomach Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA topoisomerase I inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Egl nine homolog 1 inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Liver Diseases; Anemia; Renal Insufficiency, Chronic
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Wounds and Injuries; Brain Concussion; Brain Injuries; Fragile X Syndrome; Rett Syndrome
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Acanthamoeba Keratitis; Eye Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: 20S proteosome inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Lymphoma; Neoplasms; Ependymoma; Multiple Myeloma; Glioblastoma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Phosphodiesterase 3 inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Acute Kidney Injury; Coronary Disease; Hernias, Diaphragmatic, Congenital; Ischemic Attack, Transient; Muscular Diseases; Shock, Septic; Stroke; Amyotrophic Lateral Sclerosis; Cardiovascular Diseases; Heart Failure; ST Elevation Myocardial Infarction; Severe Acute Respiratory Syndrome; Shock
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Hepatitis C virus serine protease, NS3/NS4A inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hepatitis C; Infections; Hepatitis C, Chronic
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Cocaine-Related Disorders; Atrial Flutter; Atrial Fibrillation
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Bronchial Diseases; Cough
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Kappa opioid receptor antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Anxiety; Depressive Disorder, Treatment-Resistant; Tobacco Use Disorder; Depressive Disorder, Major
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Eye Diseases; Crohn Disease; Huntington Disease; Lupus Erythematosus, Systemic; Lupus Nephritis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine D2 receptor antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Schizophrenia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Macrophage colony stimulating factor receptor inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Central Nervous System Neoplasms; Endometrial Neoplasms; Fallopian Tube Neoplasms; Glioblastoma; Kidney Neoplasms; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Macular Degeneration; Neoplasm Metastasis; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Primary Myelofibrosis; Uterine Cervical Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Lymphoma, Large B-Cell, Diffuse; Melanoma; Mesothelioma; Multiple Myeloma; Neoplasms; Neuroendocrine Tumors; Prostatic Neoplasms, Castration-Resistant; Sarcoma; von Hippel-Lindau Disease; Colonic Neoplasms; Rectal Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Norepinephrine transporter inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Attention Deficit Disorder with Hyperactivity; Fibromyalgia; Hypotension, Orthostatic; Multiple System Atrophy; Parkinson Disease
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Granulomatosis with Polyangiitis; Immune System Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Thromboxane-A synthase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Dry Eye Syndromes
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: PARP 1, 2 and 3 inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Breast Neoplasms, Male; Carcinoma; Carcinoma, Endometrioid; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Lymphoma; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Stomach Neoplasms; Astrocytoma; Carcinoma, Hepatocellular; Colorectal Neoplasms; Fallopian Tube Neoplasms; Glioblastoma; Gliosarcoma; Hemangiosarcoma; Hereditary Breast and Ovarian Cancer Syndrome; Melanoma; Prostatic Neoplasms; Rectal Neoplasms; Skin Neoplasms; Small Cell Lung Carcinoma; Testicular Neoplasms; Triple Negative Breast Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasms; Ovarian Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Carcinoma, Renal Cell; Colorectal Neoplasms; Lung Neoplasms; Melanoma; Neoplasms, Germ Cell and Embryonal; Carcinoma, Hepatocellular; Myelodysplastic Syndromes; Myeloproliferative Disorders; Ovarian Neoplasms; Small Cell Lung Carcinoma; Urinary Bladder Neoplasms; Leukemia, Myeloid, Acute
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Rectal Neoplasms; Colorectal Neoplasms; Stomach Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown