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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine D2 receptor antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Anxiety; Dementia; Depressive Disorder; Psychotic Disorders; Schizophrenia; Tourette Syndrome
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Estrogen receptor modulator
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dihydropyrimidine dehydrogenase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Head and Neck Neoplasms; Lymphoma; Neoplasms; Breast Neoplasms; Colonic Neoplasms; Colorectal Neoplasms; Rectal Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Potassium-transporting ATPase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Duodenal Ulcer; Gastroesophageal Reflux; Hemorrhage; Peptic Ulcer
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Gastritis; Gastroesophageal Reflux; Peptic Ulcer
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cyclooxygenase-2 inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Lupus Nephritis; Purpura, Thrombocytopenic, Idiopathic; Sjogren's Syndrome; Arthritis, Rheumatoid
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Fibroblast growth factor receptor inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Neoplasm Metastasis; Neoplasms; Ovarian Neoplasms; Colorectal Neoplasms; Uterine Cervical Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Liver Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Protein farnesyltransferase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Breast Neoplasms, Male; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Multiple Myeloma; Myeloproliferative Disorders; Neoplasms; Astrocytoma; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Glioblastoma; Gliosarcoma; Head and Neck Neoplasms; Inflammatory Breast Neoplasms; Leukemia, Large Granular Lymphocytic; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelomonocytic, Chronic; Leukemia, Myelomonocytic, Juvenile; Lung Neoplasms; Lymphoma, Mantle-Cell; Medulloblastoma; Melanoma; Neuroectodermal Tumors, Primitive; Oligodendroglioma; Pancreatic Neoplasms; Polycythemia Vera; Primary Myelofibrosis; Prostatic Neoplasms, Castration-Resistant; Thrombocythemia, Essential; Thyroid Neoplasms; Urinary Bladder Neoplasms; Leukemia, Erythroblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Myelodysplastic Syndromes
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Andersen Syndrome; Hypertension; Arrhythmias, Cardiac
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Neoplasms; Carcinoma, Hepatocellular; Ovarian Neoplasms; Peritoneal Neoplasms; Rhabdomyosarcoma; Small Cell Lung Carcinoma; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Lung Neoplasms; Uterine Cervical Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Fast skeletal troponin complex activator
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Intermittent Claudication; Myasthenia Gravis; Peripheral Arterial Disease; Amyotrophic Lateral Sclerosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Spinal Cord Injuries
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA cross-linking agent
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Neoplasms; Breast Neoplasms; Sarcoma; Small Cell Lung Carcinoma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Serotonin 2a (5-HT2a) receptor antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hemorrhoids
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Hepatocyte growth factor receptor inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Esophageal Neoplasms; Neoplasms; Breast Neoplasms; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Mesothelioma; Multiple Myeloma; Neoplasms, Germ Cell and Embryonal; Pancreatic Neoplasms; Prostatic Neoplasms; Small Cell Lung Carcinoma; Stomach Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Liver Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Adrenergic receptor alpha-2 antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Depressive Disorder, Major
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Tumour suppressor p53/oncoprotein Mdm2 inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Breast Neoplasms; Colorectal Neoplasms; Glioblastoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Multiple Myeloma; Thrombocythemia, Essential; Neoplasms; Polycythemia Vera; Leukemia, Myeloid, Acute
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Hydrochloric acid sequestering agent
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Osteoarthritis, Hip
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Breast Neoplasms; Colorectal Neoplasms; Ovarian Neoplasms; Ischemic Stroke
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Colitis, Ulcerative; Head and Neck Neoplasms; Arthritis, Rheumatoid; Dry Eye Syndromes; Gastritis; Gastroesophageal Reflux; Osteoarthritis; Peptic Ulcer; Spondylitis, Ankylosing; Stomach Ulcer
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sodium/glucose cotransporter 2 inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Diabetes Mellitus, Type 2; Non-alcoholic Fatty Liver Disease
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Muscle Spasticity; Arthralgia; Myalgia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Serotonin 6 (5-HT6) receptor antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Schizophrenia; Alzheimer Disease
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Epidermal growth factor receptor inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Neoplasms; Stomach Neoplasms; Adenocarcinoma of Lung; Breast Neoplasms; Esophageal Neoplasms; Head and Neck Neoplasms; Carcinoma, Non-Small-Cell Lung
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Adenosine A1 receptor antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Liver Diseases; Heart Failure; Renal Insufficiency
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Epidermal growth factor receptor erbB1 inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Pancreatic Neoplasms; Adenocarcinoma of Lung; Breast Neoplasms; Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Esophageal Neoplasms; Nasopharyngeal Neoplasms; Psoriasis; Carcinoma, Non-Small-Cell Lung; Lung Neoplasms; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Respiratory Insufficiency; Coronary Disease; Heart Failure; Heart Failure, Systolic; Menopause; Prostatic Neoplasms; Pancreatitis; Reperfusion Injury
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Retinoic acid receptor gamma agonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Dry Eye Syndromes; Myositis Ossificans
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Leishmaniasis; Trypanosomiasis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Complement factor B inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Liver Diseases; Glomerulonephritis; Glomerulonephritis, Membranous; Lupus Nephritis; Macular Degeneration; Atypical Hemolytic Uremic Syndrome; Glomerulonephritis, IGA
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Adenosine A1 receptor agonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Glaucoma, Open-Angle; Ocular Hypertension
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Neurokinin 1 receptor antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Pruritus; Alcoholism; Phobia, Social; Dermatitis, Atopic; Gastroparesis; Motion Sickness; Severe Acute Respiratory Syndrome
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Cough; Inflammation; Rhinitis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown