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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Estrogen receptor beta agonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Liver Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hyperparathyroidism, Secondary
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Endothelin receptor ET-A antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hypertension; Glomerulonephritis, IGA; Glomerulosclerosis, Focal Segmental
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Nausea
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Voltage-gated L-type calcium channel blocker
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Alzheimer Disease; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Estrogen receptor alpha modulator
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hypogonadism; Obesity
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Kidney Neoplasms; Lung Neoplasms; Melanoma; Neoplasms; Skin Neoplasms; Carcinoma, Non-Small-Cell Lung
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: PI3-kinase class I inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Kidney Diseases; Leukemia; Liver Diseases; Lung Neoplasms; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Primary Myelofibrosis; Small Cell Lung Carcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Endometrial Neoplasms; Esophageal Neoplasms; Glioblastoma; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Mantle-Cell; Melanoma; Neoplasms; Prostatic Neoplasms, Castration-Resistant; Thymoma; Thyroid Neoplasms; Uterine Cervical Neoplasms; Breast Neoplasms; Head and Neck Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Common Cold; Prostatic Neoplasms, Castration-Resistant
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial dihydrofolate reductase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Severe Acute Respiratory Syndrome; Tuberculosis; Bacterial Infections; Peritonitis; Sepsis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Lymphoma, Large B-Cell, Diffuse; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Neuroendocrine Tumors
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Adrenergic receptor alpha-1 antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine D2 receptor antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Digestive System Diseases; Dyspepsia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Retinoic acid receptor alpha agonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Pancreatic Neoplasms; Alzheimer Disease; Crohn Disease; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Lupus Nephritis; Paraparesis, Tropical Spastic; Myelodysplastic Syndromes
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Leukemia, Myeloid, Acute
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Carbonic anhydrase I inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Osteoarthritis; Osteoarthritis, Knee; Osteoarthritis, Hip; Rheumatic Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Cystinuria; Gout; Arthritis, Rheumatoid; Rheumatic Diseases; Severe Acute Respiratory Syndrome
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Heat shock protein HSP90 inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Burkitt Lymphoma; Chondrosarcoma; Colorectal Neoplasms; Head and Neck Neoplasms; Immunoblastic Lymphadenopathy; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Prolymphocytic; Leukemia-Lymphoma, Adult T-Cell; Lung Neoplasms; Lymphoma; Lymphoma, AIDS-Related; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Mycosis Fungoides; Osteosarcoma; Ovarian Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms, Castration-Resistant; Sezary Syndrome; Stomach Neoplasms; Urinary Bladder Neoplasms; Waldenstrom Macroglobulinemia; Breast Neoplasms; Carcinoma, Medullary; Hodgkin Disease; Kidney Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Melanoma; Myeloproliferative Disorders; Neoplasms; Prostatic Neoplasms; Thyroid Neoplasms; Multiple Myeloma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cannabinoid CB1 receptor inverse agonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Tobacco Use Disorder; Urinary Incontinence; Diabetes Mellitus, Type 2; Obesity
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hepatitis C, Chronic
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Anxiety; Dementia; Depressive Disorder; Schizophrenia; Sleep Initiation and Maintenance Disorders; Sleep Wake Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Voltage-gated potassium channel blocker
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: PI3-kinase class I inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Lung Neoplasms; Lymphoma, Non-Hodgkin; Carcinoma, Squamous Cell; Multiple Myeloma; Breast Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Carcinoma, Renal Cell; Leukemia, Myeloid, Acute; Lymphoma; Neoplasms; Thrombocythemia, Essential; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Fallopian Tube Neoplasms; Melanoma; Ovarian Neoplasms; Sarcoma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Multiple Myeloma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Atrial Fibrillation; Thrombosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Asthma; Lung Diseases, Obstructive
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Metabotropic glutamate receptor 2 agonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Amphetamine-Related Disorders; Psychotic Disorders; Stress Disorders, Post-Traumatic; Schizophrenia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Neurokinin 2 receptor antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Anxiety; Depressive Disorder; Depressive Disorder, Major
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown