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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Fibroblast growth factor receptor inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasms; Urinary Bladder Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Epilepsy, Reflex
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Depressive Disorder, Major; Huntington Disease; Nervous System Diseases; Multiple Sclerosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Calcium sensing receptor antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Fractures, Bone; Osteoporosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Central Nervous System Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Multiple Myeloma; Adrenal Cortex Neoplasms; Gliosarcoma; Small Cell Lung Carcinoma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Serotonin 7 (5-HT7) receptor antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Bipolar Disorder; Depressive Disorder, Major
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Rhinitis, Allergic, Seasonal
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Ephrin type-B receptor 4 inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Colonic Neoplasms; Neoplasms; Ovarian Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Essential Hypertension; Hypertension
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Brain Neoplasms; Glioblastoma; Lymphoma; Oligodendroglioma; Cholangiocarcinoma; Colorectal Neoplasms; Stomatitis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Nonstructural protein 5A inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hepatitis C; Hepatitis C, Chronic
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Neoplasms; Prostatic Neoplasms, Castration-Resistant
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 activator
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Heart Failure; Shock
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Tubulin stabiliser
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Glioblastoma; Melanoma; Ovarian Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: RAS inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Kinesin-like protein 1 inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Colonic Neoplasms; Liver Neoplasms; Melanoma; Ovarian Neoplasms; Prostatic Neoplasms; Rectal Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: GPI-anchored wall transfer protein 1 inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Leukemia, Myeloid, Acute; Candidemia; Mycoses
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Nonstructural protein 5A inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hepatitis C; Hepatitis C, Chronic
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Carcinoma, Renal Cell; Anemia, Sickle Cell; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Serine/threonine-protein kinase mTOR inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Carcinoma, Endometrioid; Carcinoma, Hepatocellular; Carcinoma, Merkel Cell; Cystadenoma, Serous; Fallopian Tube Neoplasms; Glioblastoma; Gliosarcoma; Lymphoma; Multiple Myeloma; Neoplasms; Waldenstrom Macroglobulinemia; Breast Neoplasms; Carcinoma, Islet Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Endometrial Neoplasms; Leukemia, Biphenotypic, Acute; Neuroendocrine Tumors; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Thyroid Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Depressive Disorder, Major; Schizophrenia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Orexin receptor 1 antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Sleep Initiation and Maintenance Disorders; Sleep Wake Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Vanilloid receptor antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Dermatitis, Atopic; Irritable Bowel Syndrome; Migraine Disorders; Rhinitis; Toothache
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Serotonin 7 (5-HT7) receptor antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine D2 receptor antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cyclin-dependent kinase 1 inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Breast Neoplasms; Neoplasms; Carcinoma, Non-Small-Cell Lung; Cystic Fibrosis; Pituitary ACTH Hypersecretion
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: MAP kinase p38 alpha inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Crohn Disease
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hepatitis C; Hepatitis C, Chronic
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Steryl-sulfatase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Endometrial Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Breast Neoplasms; Breast Neoplasms, Male; Neoplasms; Prostatic Neoplasms, Castration-Resistant
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial DNA gyrase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Bacterial Infections; Tuberculosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Leishmaniasis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA cross-linking agent
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Microsomal triglyceride transfer protein inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Diabetes Mellitus, Type 2; Hyperlipidemias; Hyperlipoproteinemia Type I; Hypertriglyceridemia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Neoplasms; Lung Neoplasms; Sarcoma