SALVIANOLIC ACID A

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Search structure


Synonyms	Dan phenolic acid a Salvianolic acid a
Status
Molecule Category	Free-form
UNII	51622542XO

Structure


InChI Key	YMGFTDKNIWPMGF-UCPJVGPRSA-N
Smiles	O=C(/C=C/c1ccc(O)c(O)c1/C=C/c1ccc(O)c(O)c1)O[C@H](Cc1ccc(O)c(O)c1)C(=O)O
InChI	InChI=1S/C26H22O10/c27-18-7-2-14(11-21(18)30)1-6-17-16(4-9-20(29)25(17)33)5-10-24(32)36-23(26(34)35)13-15-3-8-19(28)22(31)12-15/h1-12,23,27-31,33H,13H2,(H,34,35)/b6-1+,10-5+/t23-/m1/s1

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C26H22O10
Molecular Weight	494.45
AlogP	3.34
Hydrogen Bond Acceptor	9.0
Hydrogen Bond Donor	7.0
Number of Rotational Bond	8.0
Polar Surface Area	184.98
Molecular species	ACID
Aromatic Rings	3.0
Heavy Atoms	36.0

Pharmacology

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Enzyme Lyase	-	-	-	39.8-71.4	-
Transcription factor	-	-	-	-	30.2-41

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Homo sapiens	-	-	-	39.8-71.4	-

Cross References

Resources	Reference
ChEBI	9017
ChEMBL	CHEMBL457077
DrugBank	DB15246
FDA SRS	51622542XO
KEGG	C10492
PubChem	5281793
SureChEMBL	SCHEMBL19235589
ZINC	ZINC000004098737

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025