MACIMORELIN ACETATE

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Trade Names
Synonyms
Status
Molecule Category Salt-form
UNII AQZ1003RMG
EPA CompTox DTXSID40241516
Parent Compound: MACIMORELIN

Structure

InChI Key WVDSKQXKCDZXLH-OHIDFYLOSA-N
Smiles CC(=O)O.CC(C)(N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1c[nH]c2ccccc12)NC=O
InChI
InChI=1S/C26H30N6O3.C2H4O2/c1-26(2,27)25(35)31-22(11-16-13-28-20-9-5-3-7-18(16)20)24(34)32-23(30-15-33)12-17-14-29-21-10-6-4-8-19(17)21;1-2(3)4/h3-10,13-15,22-23,28-29H,11-12,27H2,1-2H3,(H,30,33)(H,31,35)(H,32,34);1H3,(H,3,4)/t22-,23-;/m1./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C28H34N6O5
Molecular Weight 534.62
AlogP 1.84
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 6.0
Number of Rotational Bond 10.0
Polar Surface Area 144.9
Molecular species NEUTRAL
Aromatic Rings 4.0
Heavy Atoms 35.0

Pharmacology

Mechanism of Action Action Reference
Ghrelin receptor agonist AGONIST Wikipedia PubMed PubMed Other FDA

Target Conservation

Protein: Ghrelin receptor
Description: Growth hormone secretagogue receptor type 1
Organism : Homo sapiens
Q92847 ENSG00000121853

Cross References

Resources Reference
ChEMBL CHEMBL2364617
FDA SRS AQZ1003RMG
PubChem 71526737
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