DORZOLAMIDE HYDROCHLORIDE

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Trade Names
Synonyms
Status
Molecule Category Salt-form
UNII QZO5366EW7
EPA CompTox DTXSID1045530
Parent Compound: DORZOLAMIDE

Structure

InChI Key OSRUSFPMRGDLAG-QMGYSKNISA-N
Smiles CCN[C@H]1C[C@H](C)S(=O)(=O)c2sc(S(N)(=O)=O)cc21.Cl
InChI
InChI=1S/C10H16N2O4S3.ClH/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16;/h5-6,8,12H,3-4H2,1-2H3,(H2,11,15,16);1H/t6-,8-;/m0./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C10H17ClN2O4S3
Molecular Weight 360.91
AlogP 0.61
Hydrogen Bond Acceptor 6.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 3.0
Polar Surface Area 106.33
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 19.0

Pharmacology

Mechanism of Action Action Reference
Carbonic anhydrase II inhibitor INHIBITOR DailyMed

Target Conservation

Protein: Carbonic anhydrase II
Description: Carbonic anhydrase 2
Organism : Homo sapiens
P00918 ENSG00000104267

Cross References

Resources Reference
ChEBI 4703
ChEMBL CHEMBL1201162
FDA SRS QZO5366EW7
PubChem 6918132
SureChEMBL SCHEMBL41152
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