ACETAZOLAMIDE SODIUM

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Trade Names
Synonyms
Status
Molecule Category Salt-form
UNII 429ZT169UH
EPA CompTox DTXSID00162031
Parent Compound: ACETAZOLAMIDE

Structure

InChI Key MRSXAJAOWWFZJJ-UHFFFAOYSA-M
Smiles CC(=O)Nc1nnc(S([NH-])(=O)=O)s1.[Na+]
InChI
InChI=1S/C4H6N4O3S2.Na/c1-2(9)6-3-7-8-4(12-3)13(5,10)11;/h1H3,(H3,5,6,7,9,10,11);/q;+1/p-1

Physicochemical Descriptors

Property Name Value
Molecular Formula C4H5N4NaO3S2
Molecular Weight 244.23
AlogP -0.86
Hydrogen Bond Acceptor 6.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 2.0
Polar Surface Area 115.04
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 13.0

Pharmacology

Mechanism of Action Action Reference
Carbonic anhydrase I inhibitor INHIBITOR PubMed PubMed

Target Conservation

Protein: Carbonic anhydrase XII
Description: Carbonic anhydrase 12
Organism : Homo sapiens
O43570 ENSG00000074410
Protein: Carbonic anhydrase I
Description: Carbonic anhydrase 1
Organism : Homo sapiens
P00915 ENSG00000133742
Protein: Carbonic anhydrase II
Description: Carbonic anhydrase 2
Organism : Homo sapiens
P00918 ENSG00000104267
Protein: Carbonic anhydrase IV
Description: Carbonic anhydrase 4
Organism : Homo sapiens
P22748 ENSG00000167434

Cross References

Resources Reference
ChEBI 31163
ChEMBL CHEMBL1200814
FDA SRS 429ZT169UH
PubChem 13290219
SureChEMBL SCHEMBL40813
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