EcoDrugPlus

Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Gamma

Ensembl ID : ENSG00000105851
Gene: PIK3CG
Gene Synonyms:
32 APIs:
18 Enzyme and pathways 8 Cross references
215 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Phosphodiesterase 10a

Ensembl ID : ENSG00000112541
Gene: PDE10A
Gene Synonyms:
3 APIs:
8 Enzyme and pathways 8 Cross references
207 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Phosphodiesterase 3a

Ensembl ID : ENSG00000172572
Gene: PDE3A
Gene Synonyms: CGI-PDE
13 APIs:
4 Enzyme and pathways 8 Cross references
258 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Phosphodiesterase 3b

Ensembl ID : ENSG00000152270
Gene: PDE3B
Gene Synonyms: HCGIP1
8 APIs:
14 Enzyme and pathways 7 Cross references
204 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Phosphodiesterase 4a

Ensembl ID : ENSG00000065989
Gene: PDE4A
Gene Synonyms: DPDE2
23 APIs:
7 Enzyme and pathways 7 Cross references
250 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Phosphodiesterase 4b

Ensembl ID : ENSG00000184588
Gene: PDE4B
Gene Synonyms: DPDE4
23 APIs:
6 Enzyme and pathways 7 Cross references
298 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Phosphodiesterase 4c

Ensembl ID : ENSG00000105650
Gene: PDE4C
Gene Synonyms: DPDE1
23 APIs:
7 Enzyme and pathways 7 Cross references
88 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Phosphodiesterase 4d

Ensembl ID : ENSG00000113448
Gene: PDE4D
Gene Synonyms: DPDE3
24 APIs:
7 Enzyme and pathways 8 Cross references
235 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Phosphodiesterase 5a

Ensembl ID : ENSG00000138735
Gene: PDE5A
Gene Synonyms:
8 APIs:
12 Enzyme and pathways 7 Cross references
208 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Phosphodiesterase 7a

Ensembl ID : ENSG00000205268
Gene: PDE7A
Gene Synonyms: HCP1
1 APIs:
4 Enzyme and pathways 7 Cross references
240 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Phosphodiesterase 7b

Ensembl ID : ENSG00000171408
Gene: PDE7B
Gene Synonyms:
1 APIs:
4 Enzyme and pathways 7 Cross references
174 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Phosphodiesterase 9a

Ensembl ID : ENSG00000160191
Gene: PDE9A
Gene Synonyms:
2 APIs:
4 Enzyme and pathways 7 Cross references
193 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Select Keywords:


PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains. Elements of the website have been developed under projects PREMIER and the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains.

Elements of the website have been developed under projects PREMIER and the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).