EcoDrugPlus

Mitogen-Activated Protein Kinase Kinase Kinase 11

Ensembl ID : ENSG00000173327
Gene: MAP3K11
Gene Synonyms: MEKK11,MLK3,PTK1,SPRK
1 APIs:
18 Enzyme and pathways 7 Cross references
184 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Mitogen-Activated Protein Kinase Kinase Kinase 12

Ensembl ID : ENSG00000139625
Gene: MAP3K12
Gene Synonyms: DLK,MEKK12,MUK,ZPK,ZPKP1
1 APIs:
7 Cross references
254 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Mitogen-Activated Protein Kinase Kinase Kinase 13

Ensembl ID : ENSG00000073803
Gene: MAP3K13
Gene Synonyms: LZK,MEKK13
1 APIs:
7 Cross references
201 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Mitogen-Activated Protein Kinase Kinase Kinase 5

Ensembl ID : ENSG00000197442
Gene: MAP3K5
Gene Synonyms: ASK1,MAPKKK5,MEKK5
1 APIs:
4 Enzyme and pathways 7 Cross references
209 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Mitogen-Activated Protein Kinase Kinase Kinase 9

Ensembl ID : ENSG00000006432
Gene: MAP3K9
Gene Synonyms: MEKK9,MLK1,PRKE1
1 APIs:
7 Cross references
195 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Monoamine Oxidase A

Ensembl ID : ENSG00000189221
Gene: MAOA
Gene Synonyms:
13 APIs:
23 Enzyme and pathways 8 Cross references
148 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Monoamine Oxidase B

Ensembl ID : ENSG00000069535
Gene: MAOB
Gene Synonyms:
14 APIs:
5 Enzyme and pathways 7 Cross references
333 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Monoglyceride Lipase

Ensembl ID : ENSG00000074416
Gene: MGLL
Gene Synonyms: HU-K5,MAGL,MGL
1 APIs:
15 Enzyme and pathways 7 Cross references
209 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Motilin Receptor

Ensembl ID : ENSG00000102539
Gene: MLNR
Gene Synonyms: GPR38
3 APIs:
7 Enzyme and pathways 7 Cross references
163 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Myeloperoxidase

Ensembl ID : ENSG00000005381
Gene: MPO
Gene Synonyms:
1 APIs:
5 Enzyme and pathways 9 Cross references
182 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Natriuretic Peptide Receptor 1

Ensembl ID : ENSG00000169418
Gene: NPR1
Gene Synonyms: ANPA,ANPRA,GUCY2A,NPRA
3 APIs:
3 Enzyme and pathways 7 Cross references
186 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Natriuretic Peptide Receptor 2

Ensembl ID : ENSG00000159899
Gene: NPR2
Gene Synonyms: AMDM,ANPB,ANPRB,GC-B,GUCY2B,NPRB
1 APIs:
3 Enzyme and pathways 8 Cross references
260 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

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PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains. Elements of the website have been developed under projects PREMIER and the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains.

Elements of the website have been developed under projects PREMIER and the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).