EcoDrugPlus

Histone Deacetylase 6

Ensembl ID : ENSG00000094631
Gene: HDAC6
Gene Synonyms: FLJ16239,HD6,JM21,KIAA0901,PPP1R90
10 APIs:
30 Enzyme and pathways 8 Cross references
183 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Histone Deacetylase 7

Ensembl ID : ENSG00000061273
Gene: HDAC7
Gene Synonyms: DKFZP586J0917,HDAC7A
8 APIs:
24 Enzyme and pathways 7 Cross references
263 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Histone Deacetylase 8

Ensembl ID : ENSG00000147099
Gene: HDAC8
Gene Synonyms: HDACL1,KDAC8,MRXS6,RPD3,WTS
9 APIs:
26 Enzyme and pathways 8 Cross references
204 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Histone Deacetylase 9

Ensembl ID : ENSG00000048052
Gene: HDAC9
Gene Synonyms: HD7,HDAC,HDAC7B,KIAA0744,MITR
8 APIs:
15 Enzyme and pathways 7 Cross references
233 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Hydroxycarboxylic Acid Receptor 2

Ensembl ID : ENSG00000182782
Gene: HCAR2
Gene Synonyms: GPR109A,HCA2,HM74A,NIACR1,PUMA-G,PUMAG
1 APIs:
7 Enzyme and pathways 7 Cross references
160 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Hydroxysteroid 11-Beta Dehydrogenase 1

Ensembl ID : ENSG00000117594
Gene: HSD11B1
Gene Synonyms: HSD11,HSD11B,SDR26C1
5 APIs:
7 Enzyme and pathways 8 Cross references
267 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4

Ensembl ID : ENSG00000138622
Gene: HCN4
Gene Synonyms:
3 APIs:
3 Enzyme and pathways 8 Cross references
288 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Hypocretin Receptor 1

Ensembl ID : ENSG00000121764
Gene: HCRTR1
Gene Synonyms: ORXR1,OX1R,OXR1
2 APIs:
8 Enzyme and pathways 7 Cross references
95 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Hypocretin Receptor 2

Ensembl ID : ENSG00000137252
Gene: HCRTR2
Gene Synonyms: ORXR2,OX2R,OXR2
3 APIs:
8 Enzyme and pathways 7 Cross references
199 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Indoleamine 2,3-Dioxygenase 1

Ensembl ID : ENSG00000131203
Gene: IDO1
Gene Synonyms: IDO,INDO
2 APIs:
3 Enzyme and pathways 7 Cross references
98 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Beta

Ensembl ID : ENSG00000104365
Gene: IKBKB
Gene Synonyms: IKK-BETA,IKK2,IKKB,NFKBIKB
7 APIs:
72 Enzyme and pathways 9 Cross references
197 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Inosine Monophosphate Dehydrogenase 1

Ensembl ID : ENSG00000106348
Gene: IMPDH1
Gene Synonyms: LCA11,RP10,SWSS2608
8 APIs:
13 Enzyme and pathways 8 Cross references
271 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Select Keywords:


PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains. Elements of the website have been developed under projects PREMIER and the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains.

Elements of the website have been developed under projects PREMIER and the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).