EcoDrugPlus

Heat Shock Protein 90 Alpha Family Class B Member 1

Ensembl ID : ENSG00000096384
Gene: HSP90AB1
Gene Synonyms: HSPC2,HSPCB
9 APIs:
53 Enzyme and pathways 7 Cross references
198 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

High Mobility Group Box 1

Ensembl ID : ENSG00000189403
Gene: HMGB1
Gene Synonyms: DKFZP686A04236,HMG1,HMG3,SBP-1
1 APIs:
43 Enzyme and pathways 7 Cross references
253 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Histamine Receptor H1

Ensembl ID : ENSG00000196639
Gene: HRH1
Gene Synonyms:
68 APIs:
8 Enzyme and pathways 7 Cross references
186 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Histamine Receptor H2

Ensembl ID : ENSG00000113749
Gene: HRH2
Gene Synonyms:
12 APIs:
8 Enzyme and pathways 7 Cross references
249 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Histamine Receptor H3

Ensembl ID : ENSG00000101180
Gene: HRH3
Gene Synonyms: GPCR97
16 APIs:
6 Enzyme and pathways 7 Cross references
117 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Histamine Receptor H4

Ensembl ID : ENSG00000134489
Gene: HRH4
Gene Synonyms: AXOR35,GPCR105,GPRV53,H4R,HH4R
3 APIs:
8 Enzyme and pathways 7 Cross references
104 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Histone Deacetylase 1

Ensembl ID : ENSG00000116478
Gene: HDAC1
Gene Synonyms: GON-10,HD1,KDAC1,RPD3L1
10 APIs:
84 Enzyme and pathways 7 Cross references
252 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Histone Deacetylase 10

Ensembl ID : ENSG00000100429
Gene: HDAC10
Gene Synonyms: DKFZP761B039
8 APIs:
18 Enzyme and pathways 7 Cross references
181 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Histone Deacetylase 11

Ensembl ID : ENSG00000163517
Gene: HDAC11
Gene Synonyms:
9 APIs:
15 Enzyme and pathways 7 Cross references
198 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Histone Deacetylase 2

Ensembl ID : ENSG00000196591
Gene: HDAC2
Gene Synonyms: KDAC2,RPD3,YAF1
10 APIs:
57 Enzyme and pathways 7 Cross references
203 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Histone Deacetylase 3

Ensembl ID : ENSG00000171720
Gene: HDAC3
Gene Synonyms: HD3,KDAC3,RPD3,RPD3-2
10 APIs:
66 Enzyme and pathways 7 Cross references
156 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Histone Deacetylase 5

Ensembl ID : ENSG00000108840
Gene: HDAC5
Gene Synonyms: FLJ90614,KIAA0600,NY-CO-9
8 APIs:
19 Enzyme and pathways 7 Cross references
194 Possible Orthologues:


Display Options: Drug type Mechanism of Action Route of Adminstration Status Therapeutic Area Therapeutic Indication

Select Keywords:


PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains. Elements of the website have been developed under projects PREMIER and the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains.

Elements of the website have been developed under projects PREMIER and the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).