Gene: MKNK2
Ensembl ID : ENSG00000099875
Description: MAPK interacting serine/threonine kinase 2
Gene Synonyms: GPRK7,MNK2
1 APIs:
221 Possible Orthologues:

Expression Atlas ENSG00000099875
NCBI gene (formerly Entrezgene) 2872
GeneCards 7111
HGNC Symbol HGNC:7111
MIM gene 605069
UniProtKB Gene Name Q9NV89
WikiGene 2872
Gene: PDGFRA
Ensembl ID : ENSG00000134853
Description: platelet derived growth factor receptor alpha
Gene Synonyms: CD140A,GAS9,PDGFR2
29 APIs:
204 Possible Orthologues:

RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by PDGF R-HSA-186797
PI3K/AKT Signaling in Cancer R-HSA-2219528
Sunitinib-resistant PDGFR mutants R-HSA-9674401
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Imatinib-resistant PDGFR mutants R-HSA-9674396
Drug resistance of PDGFR mutants R-HSA-9674415
MAPK family signaling cascades R-HSA-5683057
PDGFR mutants bind TKIs R-HSA-9674428
MAPK1/MAPK3 signaling R-HSA-5684996
Disease R-HSA-1643685
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream signal transduction R-HSA-186763
Signaling by PDGFR in disease R-HSA-9671555
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Regorafenib-resistant PDGFR mutants R-HSA-9674403
Intracellular signaling by second messengers R-HSA-9006925
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Downstream signal transduction R-HSA-186763
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Sunitinib-resistant PDGFR mutants R-HSA-9674401
RAF/MAP kinase cascade R-HSA-5673001
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Regorafenib-resistant PDGFR mutants R-HSA-9674403
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI3K/AKT Signaling in Cancer R-HSA-2219528
Disease R-HSA-1643685
PDGFR mutants bind TKIs R-HSA-9674428
Imatinib-resistant PDGFR mutants R-HSA-9674396
PIP3 activates AKT signaling R-HSA-1257604
Signaling by PDGFR in disease R-HSA-9671555
Drug resistance of PDGFR mutants R-HSA-9674415
Signaling by PDGF R-HSA-186797
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
RAF/MAP kinase cascade R-HSA-5673001
PI3K/AKT Signaling in Cancer R-HSA-2219528
PIP3 activates AKT signaling R-HSA-1257604
Signal Transduction R-HSA-162582
Signaling by PDGF R-HSA-186797
Signaling by PDGFR in disease R-HSA-9671555
Downstream signal transduction R-HSA-186763
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK family signaling cascades R-HSA-5683057
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Negative regulation of the PI3K/AKT network R-HSA-199418
Imatinib-resistant PDGFR mutants R-HSA-9674396
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PDGFR mutants bind TKIs R-HSA-9674428
Disease R-HSA-1643685
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Regorafenib-resistant PDGFR mutants R-HSA-9674403
Sunitinib-resistant PDGFR mutants R-HSA-9674401
Drug resistance of PDGFR mutants R-HSA-9674415
Imatinib-resistant PDGFR mutants R-HSA-9674396
PI3K/AKT Signaling in Cancer R-HSA-2219528
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Sunitinib-resistant PDGFR mutants R-HSA-9674401
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Drug resistance of PDGFR mutants R-HSA-9674415
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of the PI3K/AKT network R-HSA-199418
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Regorafenib-resistant PDGFR mutants R-HSA-9674403
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by PDGFR in disease R-HSA-9671555
PDGFR mutants bind TKIs R-HSA-9674428
Disease R-HSA-1643685
Signaling by PDGF R-HSA-186797
Sorafenib-resistant PDGFR mutants R-HSA-9674404
MAPK1/MAPK3 signaling R-HSA-5684996
Intracellular signaling by second messengers R-HSA-9006925
Downstream signal transduction R-HSA-186763
PIP3 activates AKT signaling R-HSA-1257604
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream signal transduction R-HSA-186763
Signaling by PDGF R-HSA-186797
Signaling by PDGFR in disease R-HSA-9671555
RAF/MAP kinase cascade R-HSA-5673001
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Disease R-HSA-1643685
PDGFR mutants bind TKIs R-HSA-9674428
Negative regulation of the PI3K/AKT network R-HSA-199418
Signal Transduction R-HSA-162582
Drug resistance of PDGFR mutants R-HSA-9674415
Imatinib-resistant PDGFR mutants R-HSA-9674396
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Intracellular signaling by second messengers R-HSA-9006925
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Sunitinib-resistant PDGFR mutants R-HSA-9674401
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI3K/AKT Signaling in Cancer R-HSA-2219528
Regorafenib-resistant PDGFR mutants R-HSA-9674403
MAPK family signaling cascades R-HSA-5683057
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PIP3 activates AKT signaling R-HSA-1257604
Signaling by PDGFR in disease R-HSA-9671555
Downstream signal transduction R-HSA-186763
Sunitinib-resistant PDGFR mutants R-HSA-9674401
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI3K/AKT Signaling in Cancer R-HSA-2219528
Regorafenib-resistant PDGFR mutants R-HSA-9674403
Intracellular signaling by second messengers R-HSA-9006925
Disease R-HSA-1643685
Imatinib-resistant PDGFR mutants R-HSA-9674396
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
PDGFR mutants bind TKIs R-HSA-9674428
MAPK family signaling cascades R-HSA-5683057
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by PDGF R-HSA-186797
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
PIP3 activates AKT signaling R-HSA-1257604
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
MAPK1/MAPK3 signaling R-HSA-5684996
Drug resistance of PDGFR mutants R-HSA-9674415
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Sunitinib-resistant PDGFR mutants R-HSA-9674401
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGFR in disease R-HSA-9671555
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
PDGFR mutants bind TKIs R-HSA-9674428
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream signal transduction R-HSA-186763
Drug resistance of PDGFR mutants R-HSA-9674415
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Imatinib-resistant PDGFR mutants R-HSA-9674396
Signal Transduction R-HSA-162582
Negative regulation of the PI3K/AKT network R-HSA-199418
Regorafenib-resistant PDGFR mutants R-HSA-9674403
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by PDGF R-HSA-186797
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Disease R-HSA-1643685
RAF/MAP kinase cascade R-HSA-5673001
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGF R-HSA-186797
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Regorafenib-resistant PDGFR mutants R-HSA-9674403
Disease R-HSA-1643685
Drug resistance of PDGFR mutants R-HSA-9674415
PDGFR mutants bind TKIs R-HSA-9674428
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of the PI3K/AKT network R-HSA-199418
Sunitinib-resistant PDGFR mutants R-HSA-9674401
Downstream signal transduction R-HSA-186763
PIP3 activates AKT signaling R-HSA-1257604
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Imatinib-resistant PDGFR mutants R-HSA-9674396
MAPK family signaling cascades R-HSA-5683057
Signaling by PDGFR in disease R-HSA-9671555
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF/MAP kinase cascade R-HSA-5673001
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of the PI3K/AKT network R-HSA-199418
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream signal transduction R-HSA-186763
Sunitinib-resistant PDGFR mutants R-HSA-9674401
PI3K/AKT Signaling in Cancer R-HSA-2219528
MAPK family signaling cascades R-HSA-5683057
Drug resistance of PDGFR mutants R-HSA-9674415
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Imatinib-resistant PDGFR mutants R-HSA-9674396
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
PDGFR mutants bind TKIs R-HSA-9674428
Signaling by PDGFR in disease R-HSA-9671555
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regorafenib-resistant PDGFR mutants R-HSA-9674403
PIP3 activates AKT signaling R-HSA-1257604
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Signaling by PDGF R-HSA-186797
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RAF/MAP kinase cascade R-HSA-5673001
Drug resistance of PDGFR mutants R-HSA-9674415
PDGFR mutants bind TKIs R-HSA-9674428
MAPK1/MAPK3 signaling R-HSA-5684996
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Regorafenib-resistant PDGFR mutants R-HSA-9674403
Downstream signal transduction R-HSA-186763
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Sunitinib-resistant PDGFR mutants R-HSA-9674401
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
Sorafenib-resistant PDGFR mutants R-HSA-9674404
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Imatinib-resistant PDGFR mutants R-HSA-9674396
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Signal Transduction R-HSA-162582
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by PDGF R-HSA-186797
MAPK family signaling cascades R-HSA-5683057
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by PDGFR in disease R-HSA-9671555
Negative regulation of the PI3K/AKT network R-HSA-199418

Expression Atlas ENSG00000134853
LRG display in Ensembl gene LRG_309
NCBI gene (formerly Entrezgene) 5156
GeneCards 8803
HGNC Symbol HGNC:8803
MIM gene 173490
MIM morbid 607685
UniProtKB Gene Name P16234
WikiGene 5156
Gene: PDPK1
Ensembl ID : ENSG00000140992
Description: 3-phosphoinositide dependent protein kinase 1
Gene Synonyms: PDK1
2 APIs:
234 Possible Orthologues:

Signaling by Insulin receptor R-HSA-74752
PIP3 activates AKT signaling R-HSA-1257604
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of TP53 Degradation R-HSA-6804757
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
C-type lectin receptors (CLRs) R-HSA-5621481
Transmission across Chemical Synapses R-HSA-112315
Extra-nuclear estrogen signaling R-HSA-9009391
Regulation of TP53 Activity R-HSA-5633007
Signal Transduction R-HSA-162582
RHO GTPases activate PKNs R-HSA-5625740
ESR-mediated signaling R-HSA-8939211
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Infectious disease R-HSA-5663205
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Generic Transcription Pathway R-HSA-212436
CD28 dependent PI3K/Akt signaling R-HSA-389357
Platelet Aggregation (Plug Formation) R-HSA-76009
SARS-CoV-1-host interactions R-HSA-9692914
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RNA Polymerase II Transcription R-HSA-73857
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Transcriptional Regulation by TP53 R-HSA-3700989
Innate Immune System R-HSA-168249
VEGFR2 mediated cell proliferation R-HSA-5218921
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disease R-HSA-1643685
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Post NMDA receptor activation events R-HSA-438064
IRS-mediated signalling R-HSA-112399
Downstream TCR signaling R-HSA-202424
TCR signaling R-HSA-202403
CD28 co-stimulation R-HSA-389356
Integrin signaling R-HSA-354192
RHO GTPase Effectors R-HSA-195258
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
IGF1R signaling cascade R-HSA-2428924
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
SARS-CoV Infections R-HSA-9679506
SARS-CoV-2 Infection R-HSA-9694516
SARS-CoV-2-host interactions R-HSA-9705683
Platelet activation, signaling and aggregation R-HSA-76002
GPVI-mediated activation cascade R-HSA-114604
Costimulation by the CD28 family R-HSA-388841
SARS-CoV-1 Infection R-HSA-9678108
Regulation of TP53 Expression and Degradation R-HSA-6806003
Signaling by VEGF R-HSA-194138
Signaling by Nuclear Receptors R-HSA-9006931
Gene expression (Transcription) R-HSA-74160
Signaling by GPCR R-HSA-372790
PI3K Cascade R-HSA-109704
RSK activation R-HSA-444257
Immune System R-HSA-168256
Signaling by Rho GTPases R-HSA-194315
Adaptive Immune System R-HSA-1280218
VEGFR2 mediated vascular permeability R-HSA-5218920
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Activation of AKT2 R-HSA-165158
IRS-related events triggered by IGF1R R-HSA-2428928
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor signalling cascade R-HSA-74751
PI3K/AKT Signaling in Cancer R-HSA-2219528
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G-protein beta:gamma signalling R-HSA-397795
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Neuronal System R-HSA-112316
SARS-CoV-2-host interactions R-HSA-9705683
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Generic Transcription Pathway R-HSA-212436
Neuronal System R-HSA-112316
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Transcriptional Regulation by TP53 R-HSA-3700989
IRS-related events triggered by IGF1R R-HSA-2428928
RNA Polymerase II Transcription R-HSA-73857
VEGFR2 mediated vascular permeability R-HSA-5218920
SARS-CoV-1 Infection R-HSA-9678108
Signaling by Insulin receptor R-HSA-74752
VEGFR2 mediated cell proliferation R-HSA-5218921
Transmission across Chemical Synapses R-HSA-112315
Innate Immune System R-HSA-168249
Costimulation by the CD28 family R-HSA-388841
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
CD28 co-stimulation R-HSA-389356
GPCR downstream signalling R-HSA-388396
Regulation of TP53 Activity R-HSA-5633007
IRS-mediated signalling R-HSA-112399
Gene expression (Transcription) R-HSA-74160
ESR-mediated signaling R-HSA-8939211
Regulation of TP53 Degradation R-HSA-6804757
PI3K Cascade R-HSA-109704
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
TCR signaling R-HSA-202403
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
RSK activation R-HSA-444257
IGF1R signaling cascade R-HSA-2428924
Regulation of TP53 Expression and Degradation R-HSA-6806003
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Post NMDA receptor activation events R-HSA-438064
Intracellular signaling by second messengers R-HSA-9006925
Signaling by VEGF R-HSA-194138
Hemostasis R-HSA-109582
FCERI mediated NF-kB activation R-HSA-2871837
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
CD28 dependent PI3K/Akt signaling R-HSA-389357
CLEC7A (Dectin-1) signaling R-HSA-5607764
RHO GTPase Effectors R-HSA-195258
SARS-CoV-2 Infection R-HSA-9694516
Integrin signaling R-HSA-354192
Extra-nuclear estrogen signaling R-HSA-9009391
Platelet Aggregation (Plug Formation) R-HSA-76009
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Immune System R-HSA-168256
Signaling by GPCR R-HSA-372790
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Disease R-HSA-1643685
Platelet activation, signaling and aggregation R-HSA-76002
RHO GTPases activate PKNs R-HSA-5625740
SARS-CoV-1-host interactions R-HSA-9692914
G-protein beta:gamma signalling R-HSA-397795
PI3K/AKT Signaling in Cancer R-HSA-2219528
Infectious disease R-HSA-5663205
Signal Transduction R-HSA-162582
SARS-CoV Infections R-HSA-9679506
PIP3 activates AKT signaling R-HSA-1257604
Activation of AKT2 R-HSA-165158
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by Rho GTPases R-HSA-194315
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Signaling by Nuclear Receptors R-HSA-9006931
GPVI-mediated activation cascade R-HSA-114604
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Downstream TCR signaling R-HSA-202424
Adaptive Immune System R-HSA-1280218
VEGFA-VEGFR2 Pathway R-HSA-4420097
Insulin receptor signalling cascade R-HSA-74751
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by Insulin receptor R-HSA-74752
IRS-related events triggered by IGF1R R-HSA-2428928
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGFR2 mediated cell proliferation R-HSA-5218921
IRS-mediated signalling R-HSA-112399
VEGFA-VEGFR2 Pathway R-HSA-4420097
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signal Transduction R-HSA-162582
Insulin receptor signalling cascade R-HSA-74751
FCERI mediated NF-kB activation R-HSA-2871837
Integrin signaling R-HSA-354192
C-type lectin receptors (CLRs) R-HSA-5621481
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
RNA Polymerase II Transcription R-HSA-73857
Signaling by VEGF R-HSA-194138
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Costimulation by the CD28 family R-HSA-388841
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
SARS-CoV-1-host interactions R-HSA-9692914
RSK activation R-HSA-444257
SARS-CoV-1 Infection R-HSA-9678108
RHO GTPase Effectors R-HSA-195258
CD28 co-stimulation R-HSA-389356
Signaling by Nuclear Receptors R-HSA-9006931
Downstream TCR signaling R-HSA-202424
Immune System R-HSA-168256
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
SARS-CoV-2 Infection R-HSA-9694516
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Activation of AKT2 R-HSA-165158
PI3K Cascade R-HSA-109704
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
TCR signaling R-HSA-202403
Regulation of TP53 Degradation R-HSA-6804757
Neuronal System R-HSA-112316
Gene expression (Transcription) R-HSA-74160
Hemostasis R-HSA-109582
PIP3 activates AKT signaling R-HSA-1257604
RHO GTPases activate PKNs R-HSA-5625740
SARS-CoV-2-host interactions R-HSA-9705683
Signaling by Rho GTPases R-HSA-194315
Signaling by GPCR R-HSA-372790
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Adaptive Immune System R-HSA-1280218
VEGFR2 mediated vascular permeability R-HSA-5218920
Regulation of TP53 Activity R-HSA-5633007
GPVI-mediated activation cascade R-HSA-114604
Extra-nuclear estrogen signaling R-HSA-9009391
Generic Transcription Pathway R-HSA-212436
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Transcriptional Regulation by TP53 R-HSA-3700989
Platelet activation, signaling and aggregation R-HSA-76002
SARS-CoV Infections R-HSA-9679506
Platelet Aggregation (Plug Formation) R-HSA-76009
Post NMDA receptor activation events R-HSA-438064
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
PI3K/AKT Signaling in Cancer R-HSA-2219528
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GPCR downstream signalling R-HSA-388396
Intracellular signaling by second messengers R-HSA-9006925
Regulation of TP53 Expression and Degradation R-HSA-6806003
Transmission across Chemical Synapses R-HSA-112315
Disease R-HSA-1643685
G beta:gamma signalling through PI3Kgamma R-HSA-392451
ESR-mediated signaling R-HSA-8939211
IGF1R signaling cascade R-HSA-2428924
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
G-protein beta:gamma signalling R-HSA-397795
RHO GTPase Effectors R-HSA-195258
Platelet Aggregation (Plug Formation) R-HSA-76009
Regulation of TP53 Degradation R-HSA-6804757
SARS-CoV-1 Infection R-HSA-9678108
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
G-protein beta:gamma signalling R-HSA-397795
GPVI-mediated activation cascade R-HSA-114604
SARS-CoV-1-host interactions R-HSA-9692914
FCERI mediated NF-kB activation R-HSA-2871837
Gene expression (Transcription) R-HSA-74160
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by GPCR R-HSA-372790
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
VEGFR2 mediated cell proliferation R-HSA-5218921
Regulation of TP53 Expression and Degradation R-HSA-6806003
CD28 dependent PI3K/Akt signaling R-HSA-389357
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
C-type lectin receptors (CLRs) R-HSA-5621481
Insulin receptor signalling cascade R-HSA-74751
Activation of AKT2 R-HSA-165158
SARS-CoV-2 Infection R-HSA-9694516
CD28 co-stimulation R-HSA-389356
RNA Polymerase II Transcription R-HSA-73857
Costimulation by the CD28 family R-HSA-388841
Extra-nuclear estrogen signaling R-HSA-9009391
IRS-related events triggered by IGF1R R-HSA-2428928
Transcriptional Regulation by TP53 R-HSA-3700989
Infectious disease R-HSA-5663205
Post NMDA receptor activation events R-HSA-438064
Neuronal System R-HSA-112316
SARS-CoV-2-host interactions R-HSA-9705683
IRS-mediated signalling R-HSA-112399
RSK activation R-HSA-444257
Immune System R-HSA-168256
ESR-mediated signaling R-HSA-8939211
Transmission across Chemical Synapses R-HSA-112315
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Signaling by Nuclear Receptors R-HSA-9006931
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by VEGF R-HSA-194138
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Downstream TCR signaling R-HSA-202424
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity R-HSA-5633007
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Adaptive Immune System R-HSA-1280218
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PI3K/AKT Signaling in Cancer R-HSA-2219528
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RHO GTPases activate PKNs R-HSA-5625740
TCR signaling R-HSA-202403
IGF1R signaling cascade R-HSA-2428924
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
SARS-CoV Infections R-HSA-9679506
Signaling by Insulin receptor R-HSA-74752
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Signaling by Rho GTPases R-HSA-194315
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
PI3K Cascade R-HSA-109704
VEGFR2 mediated vascular permeability R-HSA-5218920
Platelet activation, signaling and aggregation R-HSA-76002
Innate Immune System R-HSA-168249
CLEC7A (Dectin-1) signaling R-HSA-5607764
Integrin signaling R-HSA-354192
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
GPCR downstream signalling R-HSA-388396
GPVI-mediated activation cascade R-HSA-114604
Regulation of TP53 Expression and Degradation R-HSA-6806003
C-type lectin receptors (CLRs) R-HSA-5621481
ESR-mediated signaling R-HSA-8939211
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Post NMDA receptor activation events R-HSA-438064
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
RSK activation R-HSA-444257
SARS-CoV-1 Infection R-HSA-9678108
Generic Transcription Pathway R-HSA-212436
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by GPCR R-HSA-372790
SARS-CoV-2-host interactions R-HSA-9705683
SARS-CoV-2 Infection R-HSA-9694516
PI3K Cascade R-HSA-109704
Activation of AKT2 R-HSA-165158
Signaling by Nuclear Receptors R-HSA-9006931
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Regulation of TP53 Activity R-HSA-5633007
FCERI mediated NF-kB activation R-HSA-2871837
RNA Polymerase II Transcription R-HSA-73857
SARS-CoV-1-host interactions R-HSA-9692914
Innate Immune System R-HSA-168249
Hemostasis R-HSA-109582
Disease R-HSA-1643685
Signaling by VEGF R-HSA-194138
VEGFR2 mediated cell proliferation R-HSA-5218921
Extra-nuclear estrogen signaling R-HSA-9009391
Platelet Aggregation (Plug Formation) R-HSA-76009
IRS-mediated signalling R-HSA-112399
Integrin signaling R-HSA-354192
Regulation of TP53 Degradation R-HSA-6804757
Intracellular signaling by second messengers R-HSA-9006925
TCR signaling R-HSA-202403
RHO GTPases activate PKNs R-HSA-5625740
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Platelet activation, signaling and aggregation R-HSA-76002
Adaptive Immune System R-HSA-1280218
Transcriptional Regulation by TP53 R-HSA-3700989
SARS-CoV Infections R-HSA-9679506
IRS-related events triggered by IGF1R R-HSA-2428928
Infectious disease R-HSA-5663205
CD28 dependent PI3K/Akt signaling R-HSA-389357
CD28 co-stimulation R-HSA-389356
Gene expression (Transcription) R-HSA-74160
Transmission across Chemical Synapses R-HSA-112315
G-protein beta:gamma signalling R-HSA-397795
VEGFA-VEGFR2 Pathway R-HSA-4420097
Neuronal System R-HSA-112316
Signaling by Insulin receptor R-HSA-74752
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Insulin receptor signalling cascade R-HSA-74751
VEGFR2 mediated vascular permeability R-HSA-5218920
Immune System R-HSA-168256
Costimulation by the CD28 family R-HSA-388841
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPase Effectors R-HSA-195258
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream TCR signaling R-HSA-202424
PIP3 activates AKT signaling R-HSA-1257604
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
IGF1R signaling cascade R-HSA-2428924
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Rho GTPases R-HSA-194315
CLEC7A (Dectin-1) signaling R-HSA-5607764
PI3K/AKT Signaling in Cancer R-HSA-2219528
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
CLEC7A (Dectin-1) signaling R-HSA-5607764
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
CD28 dependent PI3K/Akt signaling R-HSA-389357
RNA Polymerase II Transcription R-HSA-73857
G-protein beta:gamma signalling R-HSA-397795
Integrin signaling R-HSA-354192
Insulin receptor signalling cascade R-HSA-74751
Regulation of TP53 Degradation R-HSA-6804757
SARS-CoV-1 Infection R-HSA-9678108
Downstream TCR signaling R-HSA-202424
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
IRS-mediated signalling R-HSA-112399
TCR signaling R-HSA-202403
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Insulin receptor R-HSA-74752
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
VEGFR2 mediated vascular permeability R-HSA-5218920
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IGF1R signaling cascade R-HSA-2428924
Immune System R-HSA-168256
Activation of AKT2 R-HSA-165158
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Regulation of TP53 Activity R-HSA-5633007
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
SARS-CoV-1-host interactions R-HSA-9692914
FCERI mediated NF-kB activation R-HSA-2871837
VEGFR2 mediated cell proliferation R-HSA-5218921
Post NMDA receptor activation events R-HSA-438064
PI3K/AKT Signaling in Cancer R-HSA-2219528
Regulation of TP53 Expression and Degradation R-HSA-6806003
C-type lectin receptors (CLRs) R-HSA-5621481
RHO GTPase Effectors R-HSA-195258
CD28 co-stimulation R-HSA-389356
Hemostasis R-HSA-109582
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by Nuclear Receptors R-HSA-9006931
VEGFA-VEGFR2 Pathway R-HSA-4420097
Extra-nuclear estrogen signaling R-HSA-9009391
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Transmission across Chemical Synapses R-HSA-112315
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Innate Immune System R-HSA-168249
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Neuronal System R-HSA-112316
ESR-mediated signaling R-HSA-8939211
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
PI3K Cascade R-HSA-109704
RHO GTPases activate PKNs R-HSA-5625740
SARS-CoV Infections R-HSA-9679506
Costimulation by the CD28 family R-HSA-388841
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by VEGF R-HSA-194138
SARS-CoV-2 Infection R-HSA-9694516
SARS-CoV-2-host interactions R-HSA-9705683
Signaling by GPCR R-HSA-372790
Adaptive Immune System R-HSA-1280218
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Signaling by Rho GTPases R-HSA-194315
RSK activation R-HSA-444257
GPCR downstream signalling R-HSA-388396
Platelet Aggregation (Plug Formation) R-HSA-76009
IRS-related events triggered by IGF1R R-HSA-2428928
GPVI-mediated activation cascade R-HSA-114604
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by Rho GTPases R-HSA-194315
IGF1R signaling cascade R-HSA-2428924
CD28 co-stimulation R-HSA-389356
FCERI mediated NF-kB activation R-HSA-2871837
Transmission across Chemical Synapses R-HSA-112315
GPVI-mediated activation cascade R-HSA-114604
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Insulin receptor signalling cascade R-HSA-74751
PI3K/AKT Signaling in Cancer R-HSA-2219528
Neuronal System R-HSA-112316
VEGFA-VEGFR2 Pathway R-HSA-4420097
SARS-CoV-2 Infection R-HSA-9694516
Signaling by VEGF R-HSA-194138
Regulation of TP53 Activity R-HSA-5633007
Intracellular signaling by second messengers R-HSA-9006925
SARS-CoV Infections R-HSA-9679506
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of TP53 Expression and Degradation R-HSA-6806003
Signaling by GPCR R-HSA-372790
Activation of AKT2 R-HSA-165158
Adaptive Immune System R-HSA-1280218
RHO GTPases activate PKNs R-HSA-5625740
Signal Transduction R-HSA-162582
Integrin signaling R-HSA-354192
Disease R-HSA-1643685
Downstream TCR signaling R-HSA-202424
Signaling by Nuclear Receptors R-HSA-9006931
Extra-nuclear estrogen signaling R-HSA-9009391
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Innate Immune System R-HSA-168249
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
IRS-related events triggered by IGF1R R-HSA-2428928
ESR-mediated signaling R-HSA-8939211
RHO GTPase Effectors R-HSA-195258
VEGFR2 mediated cell proliferation R-HSA-5218921
Post NMDA receptor activation events R-HSA-438064
Costimulation by the CD28 family R-HSA-388841
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Activation of NMDA receptors and postsynaptic events R-HSA-442755
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
RSK activation R-HSA-444257
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Transcriptional Regulation by TP53 R-HSA-3700989
SARS-CoV-1-host interactions R-HSA-9692914
PIP3 activates AKT signaling R-HSA-1257604
SARS-CoV-1 Infection R-HSA-9678108
Immune System R-HSA-168256
SARS-CoV-2-host interactions R-HSA-9705683
Platelet Aggregation (Plug Formation) R-HSA-76009
IRS-mediated signalling R-HSA-112399
Infectious disease R-HSA-5663205
Hemostasis R-HSA-109582
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Gene expression (Transcription) R-HSA-74160
G-protein beta:gamma signalling R-HSA-397795
TCR signaling R-HSA-202403
Regulation of TP53 Degradation R-HSA-6804757
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
C-type lectin receptors (CLRs) R-HSA-5621481
PI3K Cascade R-HSA-109704
VEGFR2 mediated vascular permeability R-HSA-5218920
Signaling by Insulin receptor R-HSA-74752
Platelet activation, signaling and aggregation R-HSA-76002
GPCR downstream signalling R-HSA-388396
Costimulation by the CD28 family R-HSA-388841
Immune System R-HSA-168256
Insulin receptor signalling cascade R-HSA-74751
VEGFR2 mediated vascular permeability R-HSA-5218920
GPVI-mediated activation cascade R-HSA-114604
Signaling by Rho GTPases R-HSA-194315
SARS-CoV-1 Infection R-HSA-9678108
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Signaling by Insulin receptor R-HSA-74752
Platelet activation, signaling and aggregation R-HSA-76002
PIP3 activates AKT signaling R-HSA-1257604
Neuronal System R-HSA-112316
Generic Transcription Pathway R-HSA-212436
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by VEGF R-HSA-194138
Downstream TCR signaling R-HSA-202424
VEGFA-VEGFR2 Pathway R-HSA-4420097
SARS-CoV-2-host interactions R-HSA-9705683
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by GPCR R-HSA-372790
CD28 co-stimulation R-HSA-389356
Signal Transduction R-HSA-162582
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
TCR signaling R-HSA-202403
Innate Immune System R-HSA-168249
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of TP53 Degradation R-HSA-6804757
PI3K Cascade R-HSA-109704
RSK activation R-HSA-444257
Regulation of TP53 Activity R-HSA-5633007
Adaptive Immune System R-HSA-1280218
G-protein beta:gamma signalling R-HSA-397795
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Platelet Aggregation (Plug Formation) R-HSA-76009
Transcriptional Regulation by TP53 R-HSA-3700989
RHO GTPases activate PKNs R-HSA-5625740
Extra-nuclear estrogen signaling R-HSA-9009391
SARS-CoV Infections R-HSA-9679506
IRS-related events triggered by IGF1R R-HSA-2428928
GPCR downstream signalling R-HSA-388396
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
IGF1R signaling cascade R-HSA-2428924
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Integrin signaling R-HSA-354192
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Gene expression (Transcription) R-HSA-74160
IRS-mediated signalling R-HSA-112399
Hemostasis R-HSA-109582
Infectious disease R-HSA-5663205
VEGFR2 mediated cell proliferation R-HSA-5218921
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
RNA Polymerase II Transcription R-HSA-73857
RHO GTPase Effectors R-HSA-195258
Signaling by Nuclear Receptors R-HSA-9006931
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Regulation of TP53 Expression and Degradation R-HSA-6806003
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Transmission across Chemical Synapses R-HSA-112315
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
SARS-CoV-2 Infection R-HSA-9694516
Activation of AKT2 R-HSA-165158
Post NMDA receptor activation events R-HSA-438064
Disease R-HSA-1643685
SARS-CoV-1-host interactions R-HSA-9692914
CD28 dependent PI3K/Akt signaling R-HSA-389357
C-type lectin receptors (CLRs) R-HSA-5621481
ESR-mediated signaling R-HSA-8939211
CLEC7A (Dectin-1) signaling R-HSA-5607764
PI3K Cascade R-HSA-109704
Neuronal System R-HSA-112316
ESR-mediated signaling R-HSA-8939211
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Activation of AKT2 R-HSA-165158
Signal Transduction R-HSA-162582
Regulation of TP53 Degradation R-HSA-6804757
Signaling by Nuclear Receptors R-HSA-9006931
GPCR downstream signalling R-HSA-388396
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G-protein beta:gamma signalling R-HSA-397795
Gene expression (Transcription) R-HSA-74160
SARS-CoV-2 Infection R-HSA-9694516
PIP3 activates AKT signaling R-HSA-1257604
SARS-CoV-1-host interactions R-HSA-9692914
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
SARS-CoV-2-host interactions R-HSA-9705683
Platelet activation, signaling and aggregation R-HSA-76002
Insulin receptor signalling cascade R-HSA-74751
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of TP53 Activity R-HSA-5633007
IGF1R signaling cascade R-HSA-2428924
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Intracellular signaling by second messengers R-HSA-9006925
Immune System R-HSA-168256
Signaling by VEGF R-HSA-194138
Extra-nuclear estrogen signaling R-HSA-9009391
RSK activation R-HSA-444257
FCERI mediated NF-kB activation R-HSA-2871837
TCR signaling R-HSA-202403
Signaling by Rho GTPases R-HSA-194315
Costimulation by the CD28 family R-HSA-388841
Post NMDA receptor activation events R-HSA-438064
Disease R-HSA-1643685
VEGFR2 mediated cell proliferation R-HSA-5218921
Adaptive Immune System R-HSA-1280218
Integrin signaling R-HSA-354192
CD28 dependent PI3K/Akt signaling R-HSA-389357
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
RHO GTPases activate PKNs R-HSA-5625740
VEGFA-VEGFR2 Pathway R-HSA-4420097
Generic Transcription Pathway R-HSA-212436
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Innate Immune System R-HSA-168249
Transmission across Chemical Synapses R-HSA-112315
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Hemostasis R-HSA-109582
SARS-CoV-1 Infection R-HSA-9678108
Signaling by GPCR R-HSA-372790
RHO GTPase Effectors R-HSA-195258
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
GPVI-mediated activation cascade R-HSA-114604
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by Insulin receptor R-HSA-74752
Downstream TCR signaling R-HSA-202424
IRS-mediated signalling R-HSA-112399
Infectious disease R-HSA-5663205
Regulation of TP53 Expression and Degradation R-HSA-6806003
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Transcriptional Regulation by TP53 R-HSA-3700989
Platelet Aggregation (Plug Formation) R-HSA-76009
CD28 co-stimulation R-HSA-389356
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
SARS-CoV Infections R-HSA-9679506
PI3K/AKT Signaling in Cancer R-HSA-2219528
C-type lectin receptors (CLRs) R-HSA-5621481
IRS-related events triggered by IGF1R R-HSA-2428928
RNA Polymerase II Transcription R-HSA-73857
VEGFR2 mediated vascular permeability R-HSA-5218920
RNA Polymerase II Transcription R-HSA-73857
CLEC7A (Dectin-1) signaling R-HSA-5607764
SARS-CoV-2 Infection R-HSA-9694516
Adaptive Immune System R-HSA-1280218
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor signalling cascade R-HSA-74751
Platelet Aggregation (Plug Formation) R-HSA-76009
Signaling by Insulin receptor R-HSA-74752
Activation of AKT2 R-HSA-165158
PIP3 activates AKT signaling R-HSA-1257604
Transmission across Chemical Synapses R-HSA-112315
RHO GTPases activate PKNs R-HSA-5625740
ESR-mediated signaling R-HSA-8939211
GPVI-mediated activation cascade R-HSA-114604
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Transcriptional Regulation by TP53 R-HSA-3700989
Disease R-HSA-1643685
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signal Transduction R-HSA-162582
VEGFR2 mediated cell proliferation R-HSA-5218921
RHO GTPase Effectors R-HSA-195258
Costimulation by the CD28 family R-HSA-388841
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Integrin signaling R-HSA-354192
GPCR downstream signalling R-HSA-388396
Regulation of TP53 Activity R-HSA-5633007
SARS-CoV Infections R-HSA-9679506
Regulation of TP53 Degradation R-HSA-6804757
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by GPCR R-HSA-372790
Hemostasis R-HSA-109582
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Immune System R-HSA-168256
SARS-CoV-1 Infection R-HSA-9678108
SARS-CoV-2-host interactions R-HSA-9705683
Regulation of TP53 Expression and Degradation R-HSA-6806003
G-protein beta:gamma signalling R-HSA-397795
Innate Immune System R-HSA-168249
RSK activation R-HSA-444257
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
TCR signaling R-HSA-202403
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by Rho GTPases R-HSA-194315
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
SARS-CoV-1-host interactions R-HSA-9692914
Generic Transcription Pathway R-HSA-212436
Post NMDA receptor activation events R-HSA-438064
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
VEGFR2 mediated vascular permeability R-HSA-5218920
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
IGF1R signaling cascade R-HSA-2428924
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by VEGF R-HSA-194138
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
CD28 dependent PI3K/Akt signaling R-HSA-389357
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Neuronal System R-HSA-112316
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Extra-nuclear estrogen signaling R-HSA-9009391
Downstream TCR signaling R-HSA-202424
CD28 co-stimulation R-HSA-389356
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Infectious disease R-HSA-5663205
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gene expression (Transcription) R-HSA-74160
IRS-mediated signalling R-HSA-112399
C-type lectin receptors (CLRs) R-HSA-5621481
Platelet activation, signaling and aggregation R-HSA-76002
PI3K Cascade R-HSA-109704
FCERI mediated NF-kB activation R-HSA-2871837
GPVI-mediated activation cascade R-HSA-114604
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Regulation of TP53 Degradation R-HSA-6804757
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Adaptive Immune System R-HSA-1280218
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Activation of NMDA receptors and postsynaptic events R-HSA-442755
SARS-CoV-1-host interactions R-HSA-9692914
Activation of AKT2 R-HSA-165158
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
CD28 co-stimulation R-HSA-389356
G beta:gamma signalling through PI3Kgamma R-HSA-392451
PI3K/AKT Signaling in Cancer R-HSA-2219528
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SARS-CoV-2 Infection R-HSA-9694516
Hemostasis R-HSA-109582
CD28 dependent PI3K/Akt signaling R-HSA-389357
Gene expression (Transcription) R-HSA-74160
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
GPCR downstream signalling R-HSA-388396
Insulin receptor signalling cascade R-HSA-74751
PIP3 activates AKT signaling R-HSA-1257604
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
SARS-CoV Infections R-HSA-9679506
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IRS-related events triggered by IGF1R R-HSA-2428928
Immune System R-HSA-168256
Infectious disease R-HSA-5663205
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G-protein beta:gamma signalling R-HSA-397795
SARS-CoV-1 Infection R-HSA-9678108
Generic Transcription Pathway R-HSA-212436
RSK activation R-HSA-444257
CLEC7A (Dectin-1) signaling R-HSA-5607764
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity R-HSA-5633007
VEGFR2 mediated cell proliferation R-HSA-5218921
Regulation of TP53 Expression and Degradation R-HSA-6806003
Signaling by GPCR R-HSA-372790
Post NMDA receptor activation events R-HSA-438064
RHO GTPase Effectors R-HSA-195258
Platelet Aggregation (Plug Formation) R-HSA-76009
RHO GTPases activate PKNs R-HSA-5625740
Disease R-HSA-1643685
SARS-CoV-2-host interactions R-HSA-9705683
Transmission across Chemical Synapses R-HSA-112315
VEGFR2 mediated vascular permeability R-HSA-5218920
IGF1R signaling cascade R-HSA-2428924
Transcriptional Regulation by TP53 R-HSA-3700989
PI3K Cascade R-HSA-109704
Signal Transduction R-HSA-162582
TCR signaling R-HSA-202403
Neuronal System R-HSA-112316
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
IRS-mediated signalling R-HSA-112399
Integrin signaling R-HSA-354192
Extra-nuclear estrogen signaling R-HSA-9009391
Downstream TCR signaling R-HSA-202424
Signaling by VEGF R-HSA-194138
Signaling by Rho GTPases R-HSA-194315
Intracellular signaling by second messengers R-HSA-9006925
VEGFA-VEGFR2 Pathway R-HSA-4420097
ESR-mediated signaling R-HSA-8939211
Costimulation by the CD28 family R-HSA-388841
Signaling by Nuclear Receptors R-HSA-9006931
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by Insulin receptor R-HSA-74752
Platelet activation, signaling and aggregation R-HSA-76002

Expression Atlas ENSG00000140992
NCBI gene (formerly Entrezgene) 5170
GeneCards 8816
HGNC Symbol HGNC:8816
MIM gene 605213
UniProtKB Gene Name O15530
WikiGene 5170
Gene: FLT4
Ensembl ID : ENSG00000037280
Description: fms related receptor tyrosine kinase 4
Gene Synonyms: PCL,VEGFR-3,VEGFR3
46 APIs:
198 Possible Orthologues:

Signaling by VEGF R-HSA-194138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by NOTCH R-HSA-157118
Signal Transduction R-HSA-162582
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by NOTCH4 R-HSA-9013694
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH R-HSA-157118
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by VEGF R-HSA-194138
Signaling by NOTCH R-HSA-157118
Signaling by VEGF R-HSA-194138
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signal Transduction R-HSA-162582
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by NOTCH4 R-HSA-9013694
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by VEGF R-HSA-194138
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH R-HSA-157118
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694
Signaling by VEGF R-HSA-194138
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by NOTCH R-HSA-157118
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by NOTCH4 R-HSA-9013694
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by NOTCH R-HSA-157118
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signal Transduction R-HSA-162582
Signaling by VEGF R-HSA-194138
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by VEGF R-HSA-194138
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by VEGF R-HSA-194138
VEGF ligand-receptor interactions R-HSA-194313
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by NOTCH4 R-HSA-9013694
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695
Signaling by VEGF R-HSA-194138
Signaling by NOTCH R-HSA-157118
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signaling by NOTCH4 R-HSA-9013694

Expression Atlas ENSG00000037280
NCBI gene (formerly Entrezgene) 2324
GeneCards 3767
HGNC Symbol HGNC:3767
MIM gene 136352
MIM morbid 618780
UniProtKB Gene Name P35916
WikiGene 2324
Gene: FLT1
Ensembl ID : ENSG00000102755
Description: fms related receptor tyrosine kinase 1
Gene Synonyms: FLT,VEGFR1
45 APIs:
199 Possible Orthologues:

Signaling by VEGF R-HSA-194138
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGF ligand-receptor interactions R-HSA-194313
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signal Transduction R-HSA-162582
Signaling by VEGF R-HSA-194138
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signaling by VEGF R-HSA-194138
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signal Transduction R-HSA-162582
VEGF ligand-receptor interactions R-HSA-194313
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Signaling by VEGF R-HSA-194138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
VEGF ligand-receptor interactions R-HSA-194313
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGF ligand-receptor interactions R-HSA-194313
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by VEGF R-HSA-194138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Signal Transduction R-HSA-162582
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by VEGF R-HSA-194138
VEGF ligand-receptor interactions R-HSA-194313
Signaling by VEGF R-HSA-194138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signal Transduction R-HSA-162582
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signal Transduction R-HSA-162582
VEGF ligand-receptor interactions R-HSA-194313
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by VEGF R-HSA-194138
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
VEGF ligand-receptor interactions R-HSA-194313
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signal Transduction R-HSA-162582
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signaling by VEGF R-HSA-194138

Expression Atlas ENSG00000102755
LRG display in Ensembl gene LRG_425
NCBI gene (formerly Entrezgene) 2321
GeneCards 3763
HGNC Symbol HGNC:3763
MIM gene 165070
UniProtKB Gene Name P17948
WikiGene 2321
Gene: PIK3CD
Ensembl ID : ENSG00000171608
Description: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
Gene Synonyms: P110D
46 APIs:
214 Possible Orthologues:

Metabolism of lipids R-HSA-556833
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Interleukin receptor SHC signaling R-HSA-912526
PI3K/AKT Signaling in Cancer R-HSA-2219528
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
Phospholipid metabolism R-HSA-1483257
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
RET signaling R-HSA-8853659
PIP3 activates AKT signaling R-HSA-1257604
Immune System R-HSA-168256
Metabolism R-HSA-1430728
Signaling by Interleukins R-HSA-449147
Adaptive Immune System R-HSA-1280218
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Interleukin-2 family signaling R-HSA-451927
Disease R-HSA-1643685
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Regulation of signaling by CBL R-HSA-912631
Signaling by Erythropoietin R-HSA-9006335
Developmental Biology R-HSA-1266738
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
PI Metabolism R-HSA-1483255
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Cytokine Signaling in Immune system R-HSA-1280215
Negative regulation of the PI3K/AKT network R-HSA-199418
Intracellular signaling by second messengers R-HSA-9006925
Cytokine Signaling in Immune system R-HSA-1280215
PIP3 activates AKT signaling R-HSA-1257604
Metabolism R-HSA-1430728
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Regulation of signaling by CBL R-HSA-912631
PI Metabolism R-HSA-1483255
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signal Transduction R-HSA-162582
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Interleukin receptor SHC signaling R-HSA-912526
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Phospholipid metabolism R-HSA-1483257
Negative regulation of the PI3K/AKT network R-HSA-199418
RET signaling R-HSA-8853659
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Interleukin-2 family signaling R-HSA-451927
Immune System R-HSA-168256
Signaling by Erythropoietin R-HSA-9006335
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Signaling by Interleukins R-HSA-449147
Metabolism of lipids R-HSA-556833
Adaptive Immune System R-HSA-1280218
Synthesis of PIPs at the plasma membrane R-HSA-1660499
PI Metabolism R-HSA-1483255
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Disease R-HSA-1643685
Negative regulation of the PI3K/AKT network R-HSA-199418
Metabolism R-HSA-1430728
Interleukin-2 family signaling R-HSA-451927
Synthesis of PIPs at the plasma membrane R-HSA-1660499
RET signaling R-HSA-8853659
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
Phospholipid metabolism R-HSA-1483257
Axon guidance R-HSA-422475
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by Erythropoietin R-HSA-9006335
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Adaptive Immune System R-HSA-1280218
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
PI3K/AKT Signaling in Cancer R-HSA-2219528
Metabolism of lipids R-HSA-556833
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cytokine Signaling in Immune system R-HSA-1280215
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Interleukins R-HSA-449147
Regulation of signaling by CBL R-HSA-912631
Nervous system development R-HSA-9675108
Interleukin receptor SHC signaling R-HSA-912526
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Intracellular signaling by second messengers R-HSA-9006925
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Metabolism R-HSA-1430728
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Metabolism of lipids R-HSA-556833
Interleukin-2 family signaling R-HSA-451927
Phospholipid metabolism R-HSA-1483257
Regulation of signaling by CBL R-HSA-912631
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
Interleukin receptor SHC signaling R-HSA-912526
Signaling by Erythropoietin R-HSA-9006335
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
Adaptive Immune System R-HSA-1280218
PI Metabolism R-HSA-1483255
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RET signaling R-HSA-8853659
Axon guidance R-HSA-422475
Negative regulation of the PI3K/AKT network R-HSA-199418
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Developmental Biology R-HSA-1266738
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI3K/AKT Signaling in Cancer R-HSA-2219528
Metabolism R-HSA-1430728
Signaling by Interleukins R-HSA-449147
Interleukin receptor SHC signaling R-HSA-912526
Regulation of signaling by CBL R-HSA-912631
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Disease R-HSA-1643685
Interleukin-2 family signaling R-HSA-451927
PI3K/AKT Signaling in Cancer R-HSA-2219528
RET signaling R-HSA-8853659
Cytokine Signaling in Immune system R-HSA-1280215
Developmental Biology R-HSA-1266738
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Immune System R-HSA-168256
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PIP3 activates AKT signaling R-HSA-1257604
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Nervous system development R-HSA-9675108
Metabolism of lipids R-HSA-556833
Signaling by Erythropoietin R-HSA-9006335
Intracellular signaling by second messengers R-HSA-9006925
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
PI Metabolism R-HSA-1483255
Phospholipid metabolism R-HSA-1483257
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Adaptive Immune System R-HSA-1280218
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Negative regulation of the PI3K/AKT network R-HSA-199418
Axon guidance R-HSA-422475
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Signal Transduction R-HSA-162582
Signaling by Interleukins R-HSA-449147
Phospholipid metabolism R-HSA-1483257
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of signaling by CBL R-HSA-912631
Axon guidance R-HSA-422475
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Metabolism of lipids R-HSA-556833
Immune System R-HSA-168256
PIP3 activates AKT signaling R-HSA-1257604
Adaptive Immune System R-HSA-1280218
Developmental Biology R-HSA-1266738
PI Metabolism R-HSA-1483255
Interleukin-2 family signaling R-HSA-451927
RET signaling R-HSA-8853659
Intracellular signaling by second messengers R-HSA-9006925
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Signaling by Erythropoietin R-HSA-9006335
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
PI3K/AKT Signaling in Cancer R-HSA-2219528
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
Interleukin receptor SHC signaling R-HSA-912526
Metabolism R-HSA-1430728
Cytokine Signaling in Immune system R-HSA-1280215
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Nervous system development R-HSA-9675108
Interleukin-2 family signaling R-HSA-451927
Intracellular signaling by second messengers R-HSA-9006925
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Immune System R-HSA-168256
Metabolism R-HSA-1430728
PI Metabolism R-HSA-1483255
Disease R-HSA-1643685
Interleukin receptor SHC signaling R-HSA-912526
PI3K/AKT Signaling in Cancer R-HSA-2219528
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Signaling by Erythropoietin R-HSA-9006335
RET signaling R-HSA-8853659
Metabolism of lipids R-HSA-556833
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
PIP3 activates AKT signaling R-HSA-1257604
Regulation of signaling by CBL R-HSA-912631
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Adaptive Immune System R-HSA-1280218
Cytokine Signaling in Immune system R-HSA-1280215
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Interleukins R-HSA-449147
Phospholipid metabolism R-HSA-1483257
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signal Transduction R-HSA-162582
Nervous system development R-HSA-9675108
Disease R-HSA-1643685
Interleukin-2 family signaling R-HSA-451927
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Phospholipid metabolism R-HSA-1483257
Developmental Biology R-HSA-1266738
Interleukin receptor SHC signaling R-HSA-912526
RET signaling R-HSA-8853659
Axon guidance R-HSA-422475
Metabolism of lipids R-HSA-556833
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Adaptive Immune System R-HSA-1280218
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
PI Metabolism R-HSA-1483255
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
Negative regulation of the PI3K/AKT network R-HSA-199418
Regulation of signaling by CBL R-HSA-912631
Cytokine Signaling in Immune system R-HSA-1280215
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Immune System R-HSA-168256
Signaling by Erythropoietin R-HSA-9006335
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Metabolism R-HSA-1430728
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of lipids R-HSA-556833
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Regulation of signaling by CBL R-HSA-912631
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
PI Metabolism R-HSA-1483255
Signaling by Interleukins R-HSA-449147
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
RET signaling R-HSA-8853659
Axon guidance R-HSA-422475
Immune System R-HSA-168256
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PIP3 activates AKT signaling R-HSA-1257604
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
PI3K/AKT Signaling in Cancer R-HSA-2219528
Adaptive Immune System R-HSA-1280218
Signal Transduction R-HSA-162582
Interleukin-2 family signaling R-HSA-451927
Disease R-HSA-1643685
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Phospholipid metabolism R-HSA-1483257
Negative regulation of the PI3K/AKT network R-HSA-199418
Developmental Biology R-HSA-1266738
Metabolism R-HSA-1430728
Interleukin receptor SHC signaling R-HSA-912526
Cytokine Signaling in Immune system R-HSA-1280215
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Erythropoietin R-HSA-9006335
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
Signaling by Erythropoietin R-HSA-9006335
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI Metabolism R-HSA-1483255
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Interleukin receptor SHC signaling R-HSA-912526
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Developmental Biology R-HSA-1266738
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Regulation of signaling by CBL R-HSA-912631
Interleukin-2 family signaling R-HSA-451927
Phospholipid metabolism R-HSA-1483257
Disease R-HSA-1643685
RET signaling R-HSA-8853659
Negative regulation of the PI3K/AKT network R-HSA-199418
Adaptive Immune System R-HSA-1280218
Signaling by Interleukins R-HSA-449147
PI3K/AKT Signaling in Cancer R-HSA-2219528

Expression Atlas ENSG00000171608
LRG display in Ensembl gene LRG_191
NCBI gene (formerly Entrezgene) 5293
GeneCards 8977
HGNC Symbol HGNC:8977
MIM gene 602839
MIM morbid 619281
UniProtKB Gene Name O00329
WikiGene 5293
Gene: KIF5B
Ensembl ID : ENSG00000170759
Description: kinesin family member 5B
Gene Synonyms: KNS,KNS1,UKHC
2 APIs:
288 Possible Orthologues:

Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Hemostasis R-HSA-109582
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
MHC class II antigen presentation R-HSA-2132295
Adaptive Immune System R-HSA-1280218
Factors involved in megakaryocyte development and platelet production R-HSA-983231
RHO GTPase Effectors R-HSA-195258
Metabolism of proteins R-HSA-392499
Membrane Trafficking R-HSA-199991
Kinesins R-HSA-983189
Vesicle-mediated transport R-HSA-5653656
Immune System R-HSA-168256
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Insulin processing R-HSA-264876
Peptide hormone metabolism R-HSA-2980736
RHO GTPases activate KTN1 R-HSA-5625970
Signaling by ALK in cancer R-HSA-9700206
Signaling by Rho GTPases R-HSA-194315
Golgi-to-ER retrograde transport R-HSA-8856688
Disease R-HSA-1643685
Hemostasis R-HSA-109582
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Signaling by ALK in cancer R-HSA-9700206
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Peptide hormone metabolism R-HSA-2980736
Disease R-HSA-1643685
Kinesins R-HSA-983189
Signal Transduction R-HSA-162582
Adaptive Immune System R-HSA-1280218
Signaling by Rho GTPases R-HSA-194315
Metabolism of proteins R-HSA-392499
Golgi-to-ER retrograde transport R-HSA-8856688
Vesicle-mediated transport R-HSA-5653656
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Membrane Trafficking R-HSA-199991
MHC class II antigen presentation R-HSA-2132295
Insulin processing R-HSA-264876
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPases activate KTN1 R-HSA-5625970
RHO GTPase Effectors R-HSA-195258
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Immune System R-HSA-168256
Signaling by Rho GTPases R-HSA-194315
RHO GTPase Effectors R-HSA-195258
RHO GTPases activate KTN1 R-HSA-5625970
Disease R-HSA-1643685
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
MHC class II antigen presentation R-HSA-2132295
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Adaptive Immune System R-HSA-1280218
Immune System R-HSA-168256
Membrane Trafficking R-HSA-199991
Signaling by ALK in cancer R-HSA-9700206
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Kinesins R-HSA-983189
Vesicle-mediated transport R-HSA-5653656
Golgi-to-ER retrograde transport R-HSA-8856688
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Insulin processing R-HSA-264876
Hemostasis R-HSA-109582
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Immune System R-HSA-168256
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Insulin processing R-HSA-264876
Disease R-HSA-1643685
MHC class II antigen presentation R-HSA-2132295
Golgi-to-ER retrograde transport R-HSA-8856688
Adaptive Immune System R-HSA-1280218
RHO GTPases activate KTN1 R-HSA-5625970
Hemostasis R-HSA-109582
Vesicle-mediated transport R-HSA-5653656
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Signal Transduction R-HSA-162582
Kinesins R-HSA-983189
Signaling by Rho GTPases R-HSA-194315
Metabolism of proteins R-HSA-392499
Signaling by ALK in cancer R-HSA-9700206
Membrane Trafficking R-HSA-199991
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
RHO GTPase Effectors R-HSA-195258
Peptide hormone metabolism R-HSA-2980736
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Hemostasis R-HSA-109582
Kinesins R-HSA-983189
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signal Transduction R-HSA-162582
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Golgi-to-ER retrograde transport R-HSA-8856688
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
MHC class II antigen presentation R-HSA-2132295
Immune System R-HSA-168256
Metabolism of proteins R-HSA-392499
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Membrane Trafficking R-HSA-199991
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Insulin processing R-HSA-264876
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Adaptive Immune System R-HSA-1280218
Signaling by Rho GTPases R-HSA-194315
RHO GTPases activate KTN1 R-HSA-5625970
Vesicle-mediated transport R-HSA-5653656
Disease R-HSA-1643685
Peptide hormone metabolism R-HSA-2980736
Signaling by ALK in cancer R-HSA-9700206
RHO GTPase Effectors R-HSA-195258
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Membrane Trafficking R-HSA-199991
Adaptive Immune System R-HSA-1280218
RHO GTPase Effectors R-HSA-195258
Signaling by Rho GTPases R-HSA-194315
MHC class II antigen presentation R-HSA-2132295
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Peptide hormone metabolism R-HSA-2980736
Golgi-to-ER retrograde transport R-HSA-8856688
Signal Transduction R-HSA-162582
Vesicle-mediated transport R-HSA-5653656
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Insulin processing R-HSA-264876
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Immune System R-HSA-168256
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by ALK in cancer R-HSA-9700206
Kinesins R-HSA-983189
Disease R-HSA-1643685
Metabolism of proteins R-HSA-392499
Hemostasis R-HSA-109582
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by ALK fusions and activated point mutants R-HSA-9725370
RHO GTPases activate KTN1 R-HSA-5625970
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Insulin processing R-HSA-264876
Signal Transduction R-HSA-162582
Membrane Trafficking R-HSA-199991
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Adaptive Immune System R-HSA-1280218
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Kinesins R-HSA-983189
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Signaling by ALK in cancer R-HSA-9700206
Golgi-to-ER retrograde transport R-HSA-8856688
MHC class II antigen presentation R-HSA-2132295
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Hemostasis R-HSA-109582
RHO GTPase Effectors R-HSA-195258
Immune System R-HSA-168256
Signaling by Rho GTPases R-HSA-194315
Vesicle-mediated transport R-HSA-5653656
RHO GTPases activate KTN1 R-HSA-5625970
Disease R-HSA-1643685
Hemostasis R-HSA-109582
Kinesins R-HSA-983189
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MHC class II antigen presentation R-HSA-2132295
Metabolism of proteins R-HSA-392499
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Signal Transduction R-HSA-162582
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Insulin processing R-HSA-264876
Membrane Trafficking R-HSA-199991
RHO GTPase Effectors R-HSA-195258
Peptide hormone metabolism R-HSA-2980736
Signaling by Rho GTPases R-HSA-194315
RHO GTPases activate KTN1 R-HSA-5625970
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Golgi-to-ER retrograde transport R-HSA-8856688
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Immune System R-HSA-168256
Signaling by ALK in cancer R-HSA-9700206
Disease R-HSA-1643685
Vesicle-mediated transport R-HSA-5653656
Adaptive Immune System R-HSA-1280218
Golgi-to-ER retrograde transport R-HSA-8856688
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Peptide hormone metabolism R-HSA-2980736
Disease R-HSA-1643685
RHO GTPase Effectors R-HSA-195258
Adaptive Immune System R-HSA-1280218
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Kinesins R-HSA-983189
Membrane Trafficking R-HSA-199991
Immune System R-HSA-168256
Vesicle-mediated transport R-HSA-5653656
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Hemostasis R-HSA-109582
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Signaling by ALK in cancer R-HSA-9700206
Insulin processing R-HSA-264876
Signal Transduction R-HSA-162582
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Rho GTPases R-HSA-194315
Metabolism of proteins R-HSA-392499
MHC class II antigen presentation R-HSA-2132295
RHO GTPases activate KTN1 R-HSA-5625970
Adaptive Immune System R-HSA-1280218
Peptide hormone metabolism R-HSA-2980736
Insulin processing R-HSA-264876
Signal Transduction R-HSA-162582
Kinesins R-HSA-983189
MHC class II antigen presentation R-HSA-2132295
RHO GTPase Effectors R-HSA-195258
Signaling by ALK in cancer R-HSA-9700206
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Disease R-HSA-1643685
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Signaling by Rho GTPases R-HSA-194315
Immune System R-HSA-168256
RHO GTPases activate KTN1 R-HSA-5625970
Golgi-to-ER retrograde transport R-HSA-8856688
Vesicle-mediated transport R-HSA-5653656
Metabolism of proteins R-HSA-392499
Hemostasis R-HSA-109582
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Membrane Trafficking R-HSA-199991
Vesicle-mediated transport R-HSA-5653656
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442
Membrane Trafficking R-HSA-199991
Peptide hormone metabolism R-HSA-2980736
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434
Signaling by Rho GTPases R-HSA-194315
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Kinesins R-HSA-983189
RHO GTPase Effectors R-HSA-195258
Adaptive Immune System R-HSA-1280218
Immune System R-HSA-168256
Disease R-HSA-1643685
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Insulin processing R-HSA-264876
RHO GTPases activate KTN1 R-HSA-5625970
Hemostasis R-HSA-109582
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Metabolism of proteins R-HSA-392499
Signal Transduction R-HSA-162582
Golgi-to-ER retrograde transport R-HSA-8856688
MHC class II antigen presentation R-HSA-2132295
Signaling by ALK in cancer R-HSA-9700206

Expression Atlas ENSG00000170759
NCBI gene (formerly Entrezgene) 3799
GeneCards 6324
HGNC Symbol HGNC:6324
MIM gene 602809
UniProtKB Gene Name V9HW29
WikiGene 3799
Gene: KDR
Ensembl ID : ENSG00000128052
Description: kinase insert domain receptor
Gene Synonyms: CD309,FLK1,VEGFR,VEGFR2
71 APIs:
199 Possible Orthologues:

VEGFR2 mediated cell proliferation R-HSA-5218921
Signaling by VEGF R-HSA-194138
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
VEGF ligand-receptor interactions R-HSA-194313
Extracellular matrix organization R-HSA-1474244
VEGFA-VEGFR2 Pathway R-HSA-4420097
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Integrin cell surface interactions R-HSA-216083
Signaling by PDGFR in disease R-HSA-9671555
Integrin cell surface interactions R-HSA-216083
VEGFR2 mediated cell proliferation R-HSA-5218921
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGFA-VEGFR2 Pathway R-HSA-4420097
Disease R-HSA-1643685
Extracellular matrix organization R-HSA-1474244
VEGF ligand-receptor interactions R-HSA-194313
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by VEGF R-HSA-194138
Signaling by PDGFR in disease R-HSA-9671555
Signal Transduction R-HSA-162582
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGFA-VEGFR2 Pathway R-HSA-4420097
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by VEGF R-HSA-194138
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
VEGF ligand-receptor interactions R-HSA-194313
Signaling by PDGFR in disease R-HSA-9671555
Signal Transduction R-HSA-162582
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGFR2 mediated cell proliferation R-HSA-5218921
Integrin cell surface interactions R-HSA-216083
Extracellular matrix organization R-HSA-1474244
Disease R-HSA-1643685
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGFR2 mediated cell proliferation R-HSA-5218921
Signaling by VEGF R-HSA-194138
VEGFA-VEGFR2 Pathway R-HSA-4420097
Integrin cell surface interactions R-HSA-216083
VEGF ligand-receptor interactions R-HSA-194313
Extracellular matrix organization R-HSA-1474244
Disease R-HSA-1643685
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
Signal Transduction R-HSA-162582
Signaling by PDGFR in disease R-HSA-9671555
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signal Transduction R-HSA-162582
VEGFA-VEGFR2 Pathway R-HSA-4420097
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Integrin cell surface interactions R-HSA-216083
Disease R-HSA-1643685
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGFR in disease R-HSA-9671555
VEGF ligand-receptor interactions R-HSA-194313
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
VEGFR2 mediated cell proliferation R-HSA-5218921
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
Signaling by VEGF R-HSA-194138
Extracellular matrix organization R-HSA-1474244
Signaling by VEGF R-HSA-194138
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signal Transduction R-HSA-162582
VEGFR2 mediated cell proliferation R-HSA-5218921
Integrin cell surface interactions R-HSA-216083
Signaling by PDGFR in disease R-HSA-9671555
Extracellular matrix organization R-HSA-1474244
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
VEGFA-VEGFR2 Pathway R-HSA-4420097
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Disease R-HSA-1643685
Integrin cell surface interactions R-HSA-216083
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
VEGFR2 mediated cell proliferation R-HSA-5218921
Extracellular matrix organization R-HSA-1474244
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
Signaling by VEGF R-HSA-194138
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGFR in disease R-HSA-9671555
VEGF ligand-receptor interactions R-HSA-194313
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGFA-VEGFR2 Pathway R-HSA-4420097
Integrin cell surface interactions R-HSA-216083
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by PDGFR in disease R-HSA-9671555
VEGF ligand-receptor interactions R-HSA-194313
Signaling by VEGF R-HSA-194138
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
VEGFR2 mediated cell proliferation R-HSA-5218921
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGFA-VEGFR2 Pathway R-HSA-4420097
Extracellular matrix organization R-HSA-1474244
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
VEGF ligand-receptor interactions R-HSA-194313
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
VEGFR2 mediated cell proliferation R-HSA-5218921
Integrin cell surface interactions R-HSA-216083
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Signaling by VEGF R-HSA-194138
Extracellular matrix organization R-HSA-1474244
Signaling by PDGFR in disease R-HSA-9671555
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signal Transduction R-HSA-162582
VEGFA-VEGFR2 Pathway R-HSA-4420097
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGFR2 mediated cell proliferation R-HSA-5218921
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
Signaling by PDGFR in disease R-HSA-9671555
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by VEGF R-HSA-194138
Integrin cell surface interactions R-HSA-216083
VEGF ligand-receptor interactions R-HSA-194313
Extracellular matrix organization R-HSA-1474244
Disease R-HSA-1643685

Expression Atlas ENSG00000128052
LRG display in Ensembl gene LRG_1198
NCBI gene (formerly Entrezgene) 3791
GeneCards 6307
HGNC Symbol HGNC:6307
MIM gene 191306
MIM morbid 602089
UniProtKB Gene Name P35968
WikiGene 3791