4-ACETAMIDO-N-(1,2-DIHYDRO-1,2-DIOXONAPHTHALEN-4-YL)BENZAMIDE

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Molecule Category Free-form
Source Gaulton A, Kale N, van Westen GJ, Bellis LJ, Bento AP, Davies M, Hersey A, Papadatos G, Forster M, Wege P, Overington JP. A large-scale crop protection bioassay data set. Sci Data. 2015 Jul 7;2:150032. Read more ...

Structure

InChI Key ZEDIHMXSKFVJJF-UHFFFAOYSA-N
Smiles CC(=O)Nc1ccc(cc1)C(=O)NC2=CC(=O)C(=O)c3ccccc23
InChI
InChI=1S/C19H14N2O4/c1-11(22)20-13-8-6-12(7-9-13)19(25)21-16-10-17(23)18(24)15-5-3-2-4-14(15)16/h2-10H,1H3,(H,20,22)(H,21,25)

Physicochemical Descriptors

Property Name Value
Molecular Formula C19H14N2O4
Molecular Weight 334.33
AlogP 1.36
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 3.0
Polar Surface Area 92.34
Molecular species NEUTRAL
Aromatic Rings 2.0
Heavy Atoms 25.0
Assay Description Organism Bioactivity Reference
Anticonvulsant activity in Swiss albino Mus musculus (mouse) assessed as protection against subcutaneous pentylenetetrazol-induced seizures at 20 mg/kg, ip after 4 hr Mus musculus None
Anticonvulsant activity in Swiss albino Mus musculus (mouse) assessed as protection against subcutaneous pentylenetetrazol-induced seizures at 40 mg/kg, ip after 4 hr Mus musculus None
Anticonvulsant activity in Swiss albino Mus musculus (mouse) assessed as protection against subcutaneous pentylenetetrazol-induced seizures at 40 mg/kg, ip after 0.5 hr Mus musculus None
Anticonvulsant activity in Swiss albino Mus musculus (mouse) assessed as protection against subcutaneous pentylenetetrazol-induced seizures at 20 mg/kg, ip after 0.5 hr Mus musculus None
Anticonvulsant activity in Swiss albino Mus musculus (mouse) assessed as protection against maximal electroshock-induced seizures at 40 mg/kg, ip after 4 hr Mus musculus None
Anticonvulsant activity in Swiss albino Mus musculus (mouse) assessed as protection against maximal electroshock-induced seizures at 20 mg/kg, ip after 4 hr Mus musculus None
Anticonvulsant activity in Swiss albino Mus musculus (mouse) assessed as protection against maximal electroshock-induced seizures at 40 mg/kg, ip after 2 hr Mus musculus None
Anticonvulsant activity in Swiss albino Mus musculus (mouse) assessed as protection against maximal electroshock-induced seizures at 20 mg/kg, ip after 2 hr Mus musculus None
Anticonvulsant activity in Swiss albino Mus musculus (mouse) assessed as protection against maximal electroshock-induced seizures at 10 mg/kg, ip after 2 hr Mus musculus None
Anticonvulsant activity in Swiss albino Mus musculus (mouse) assessed as protection against maximal electroshock-induced seizures at 40 mg/kg, ip after 1 hr Mus musculus None
Anticonvulsant activity in Swiss albino Mus musculus (mouse) assessed as protection against maximal electroshock-induced seizures at 20 mg/kg, ip after 1 hr Mus musculus None
Anticonvulsant activity in Swiss albino Mus musculus (mouse) assessed as protection against maximal electroshock-induced seizures at 10 mg/kg, ip after 1 hr Mus musculus None

Cross References

Resources Reference
ChEMBL CHEMBL2296230
PubChem 76309428
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