1-CHLORO-N,N,N-TRIMETHYLMETHANAMINIUM 2-(4-CHLORO-2-METHYLPHENOXY)ACETATE


Source	Gaulton A, Kale N, van Westen GJ, Bellis LJ, Bento AP, Davies M, Hersey A, Papadatos G, Forster M, Wege P, Overington JP. A large-scale crop protection bioassay data set. Sci Data. 2015 Jul 7;2:150032. Read more ...


Active Pharmaceutical Ingredients Bioactive chemicals	Exact Similarity SubStructure	Threshold (%) >= 70

Structure


InChI Key	GYGWIBOQMMANDF-UHFFFAOYSA-M
Smiles	Cc1cc(Cl)ccc1OCC(=O)[O-].C[N+](C)(C)CCl
InChI	InChI=1S/C9H9ClO3.C4H11ClN/c1-6-4-7(10)2-3-8(6)13-5-9(11)12;1-6(2,3)4-5/h2-4H,5H2,1H3,(H,11,12);4H2,1-3H3/q;+1/p-1

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C13H19Cl2NO3
Molecular Weight	308.2
AlogP	None
Hydrogen Bond Acceptor	None
Hydrogen Bond Donor	None
Number of Rotational Bond	None
Polar Surface Area	None
Molecular species	None
Aromatic Rings	None
Heavy Atoms	None

Assay Description	Organism	Bioactivity
Acute toxicity in po dosed Rattus norvegicus Wistar (rat)	Rattus norvegicus	300.0 mg.kg-1
Reduction in Triticum aestivum (wheat) stem length applied at the end of tillering stage of crop measured at 4 weeks post-drug dosage	Triticum aestivum	None
Herbicidal activity against Euphorbia helioscopia measured at 4 weeks post-drug dosage	Euphorbia helioscopia	None
Herbicidal activity against Myosotis arvensis measured at 4 weeks post-drug dosage	Myosotis arvensis	None
Herbicidal activity against Centaurea cyanus measured at 4 weeks post-drug dosage	Centaurea cyanus	None
Herbicidal activity against Chenopodium album measured at 4 weeks post-drug dosage	Chenopodium album	None
Herbicidal activity against Viola arvensis measured at 4 weeks post-drug dosage	Viola arvensis	None
Herbicidal activity against Brassica napus (oilseed rape) measured at 4 weeks post-drug dosage	Brassica napus	None
Herbicidal activity against Thlaspi arvense measured at 4 weeks post-drug dosage	Thlaspi arvense	None

Cross References

Resources	Reference
ChEMBL	CHEMBL2269150
PubChem	76315878

CONTENTS


PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains. Elements of the website have been developed under projects PREMIER and the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains.

Elements of the website have been developed under projects PREMIER and the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).