BIIB-091

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Status
Molecule Category Free-form

Structure

InChI Key JSAQBOQCZJHWMA-XMMPIXPASA-N
Smiles Cn1cc(Nc2nccc(-c3ccc4c(c3)CN(C3COC3)CC[C@H]4NC(=O)c3cn(C(C)(C)C)nn3)n2)cn1
InChI
InChI=1S/C28H34N10O2/c1-28(2,3)38-15-25(34-35-38)26(39)32-24-8-10-37(21-16-40-17-21)13-19-11-18(5-6-22(19)24)23-7-9-29-27(33-23)31-20-12-30-36(4)14-20/h5-7,9,11-12,14-15,21,24H,8,10,13,16-17H2,1-4H3,(H,32,39)(H,29,31,33)/t24-/m1/s1

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Kinase Protein Kinase CMGC protein kinase group CMGC protein kinase CDKL family
- - 240 - -
Enzyme Kinase Protein Kinase Other protein kinase group Other protein kinase AUR family
- - 660 - -
Enzyme Kinase Protein Kinase STE protein kinase group STE protein kinase STE7 family
- - 200 - -
Enzyme Kinase Protein Kinase TK protein kinase group Tyrosine protein kinase Src family
- - 320 - -
Enzyme Kinase Protein Kinase TK protein kinase group Tyrosine protein kinase Tec family
- 5.4-24 0.07-240 - -
Enzyme Kinase Protein Kinase TK protein kinase group Tyrosine protein kinase Tie family
- - 40 - -
Enzyme Transferase
- - 420 - -
Membrane receptor
- 70-71 - - -
Surface antigen
- 82 - - -
EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Homo sapiens
- 1.3-82 0.07-660 - -
Mus musculus
- 57 - - -
CONTENTS