URIDINE TRIPHOSPHATE

/static/temp/default.svg Search structure
Synonyms
UTP
Status
Molecule Category Free-form
UNII UT0S826Z60
EPA CompTox DTXSID0041147

Structure

InChI Key PGAVKCOVUIYSFO-XVFCMESISA-N
Smiles O=c1ccn([C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1
InChI
InChI=1S/C9H15N2O15P3/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C9H15N2O15P3
Molecular Weight 484.14
AlogP -2.5
Hydrogen Bond Acceptor 12.0
Hydrogen Bond Donor 7.0
Number of Rotational Bond 8.0
Polar Surface Area 264.37
Molecular species ACID
Aromatic Rings 1.0
Heavy Atoms 29.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Nucleotide-like receptor (family A GPCR) Purine receptor
5.61-996 - - - -
EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Homo sapiens
5.61-996 - - - -
Rattus norvegicus
130 - - - -

Cross References

Resources Reference
ChEBI 15713
ChEMBL CHEMBL336296
DrugBank DB04005
DrugCentral 3639
FDA SRS UT0S826Z60
Human Metabolome Database HMDB0000285
Guide to Pharmacology 1734
KEGG C00075
PDB UTP
SureChEMBL SCHEMBL76682
ZINC ZINC000003861755
CONTENTS