MACROGOL


Synonyms	1,2-Ethanediol Ethylene Glycol Macrogol Polyethylene oxide
Status
Molecule Category	Free-form
ATC	A06AD15
UNII	FC72KVT52F
EPA CompTox	DTXSID8020597

Structure


InChI Key	LYCAIKOWRPUZTN-UHFFFAOYSA-N
Smiles	OCCO
InChI	InChI=1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C2H6O2
Molecular Weight	62.07
AlogP	-1.03
Hydrogen Bond Acceptor	2.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	1.0
Polar Surface Area	40.46
Molecular species	NEUTRAL
Aromatic Rings	0.0
Heavy Atoms	4.0

Pharmacology

Mechanism of Action	Action	Reference
Osmotic laxative	None	BNF

Cross References

Resources	Reference
ChEBI	30742
ChEMBL	CHEMBL457299
FDA SRS	FC72KVT52F
Human Metabolome Database	HMDB0037790
KEGG	C15588
PDB	EDO
SureChEMBL	SCHEMBL3
ZINC	ZINC000005224354

CONTENTS


PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains. Elements of the website have been developed under projects PREMIER and the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains.

Elements of the website have been developed under projects PREMIER and the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).