FENOLDOPAM MESYLATE

/static/temp/default.svg

Search structure


Synonyms	Corlopam Fendolopam mesylate Fenoldopam mesilate Fenoldopam mesylate Fenoldopam methanesulfonate NSC-759860 SK&F 82526-J SK&F-82526J SK-82526-J
Status
Molecule Category	Salt-form
UNII	HA3R0MY016

Structure


InChI Key	CVKUMNRCIJMVAR-UHFFFAOYSA-N
Smiles	CS(=O)(=O)O.Oc1ccc(C2CNCCc3c2cc(O)c(O)c3Cl)cc1
InChI	InChI=1S/C16H16ClNO3.CH4O3S/c17-15-11-5-6-18-8-13(9-1-3-10(19)4-2-9)12(11)7-14(20)16(15)21;1-5(2,3)4/h1-4,7,13,18-21H,5-6,8H2;1H3,(H,2,3,4)

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C17H20ClNO6S
Molecular Weight	401.87
AlogP	2.73
Hydrogen Bond Acceptor	4.0
Hydrogen Bond Donor	4.0
Number of Rotational Bond	1.0
Polar Surface Area	72.72
Molecular species	BASE
Aromatic Rings	2.0
Heavy Atoms	21.0

Pharmacology

Mechanism of Action	Action	Reference
Dopamine D1 receptor agonist	AGONIST	DailyMed

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Rattus norvegicus	48-57	-	-	-	-

Target Conservation


Protein: Dopamine D1 receptor Description: D(1A) dopamine receptor Organism : Homo sapiens P21728 ENSG00000184845

Cross References

Resources	Reference
ChEBI	5003
ChEMBL	CHEMBL1026
FDA SRS	HA3R0MY016
SureChEMBL	SCHEMBL41213

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025