EcoDrugPlus


Synonyms	Delpazolid LCB-01-0371 LCB-010371 Lcb01-0371
Status
Molecule Category	Free-form
UNII	43EP6XV33E

Synonyms

Delpazolid

LCB-01-0371

LCB-010371

Lcb01-0371

Status

Molecule Category

Free-form

UNII

43EP6XV33E


InChI Key	QLUWQAFDTNAYPN-LLVKDONJSA-N
Smiles	CN1CCN(c2ccc(N3C[C@H](CO)OC3=O)cc2F)C=N1
InChI	InChI=1S/C14H17FN4O3/c1-17-4-5-18(9-16-17)13-3-2-10(6-12(13)15)19-7-11(8-20)22-14(19)21/h2-3,6,9,11,20H,4-5,7-8H2,1H3/t11-/m1/s1

InChI Key

QLUWQAFDTNAYPN-LLVKDONJSA-N

Smiles

CN1CCN(c2ccc(N3C[C@H](CO)OC3=O)cc2F)C=N1

InChI

InChI=1S/C14H17FN4O3/c1-17-4-5-18(9-16-17)13-3-2-10(6-12(13)15)19-7-11(8-20)22-14(19)21/h2-3,6,9,11,20H,4-5,7-8H2,1H3/t11-/m1/s1

Property Name	Value
Molecular Formula	C14H17FN4O3
Molecular Weight	308.31
AlogP	0.84
Hydrogen Bond Acceptor	6.0
Hydrogen Bond Donor	1.0
Number of Rotational Bond	3.0
Polar Surface Area	68.61
Molecular species	NEUTRAL
Aromatic Rings	1.0
Heavy Atoms	22.0

Property Name

Value

Molecular Formula

C14H17FN4O3

Molecular Weight

308.31

AlogP

0.84

Hydrogen Bond Acceptor

6.0

Hydrogen Bond Donor

1.0

Number of Rotational Bond

3.0

Polar Surface Area

68.61

Molecular species

NEUTRAL

Aromatic Rings

1.0

Heavy Atoms

22.0

Mechanism of Action	Action	Reference
Bacterial 70S ribosome inhibitor	INHIBITOR	PubMed PubMed

Mechanism of Action

Action

Reference

Bacterial 70S ribosome inhibitor

INHIBITOR

PubMed PubMed

Resources	Reference
ChEMBL	CHEMBL1673408
DrugBank	DB13077
FDA SRS	43EP6XV33E
Guide to Pharmacology	10999
SureChEMBL	SCHEMBL11969210

Resources

Reference

ChEMBL

CHEMBL1673408

DrugBank

DB13077

FDA SRS

43EP6XV33E

Guide to Pharmacology

10999

SureChEMBL

SCHEMBL11969210

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

DELPAZOLID

Structure

Physicochemical Descriptors

Pharmacology

Cross References