OMEPRAZOLE MAGNESIUM

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Search structure


Synonyms	H 168/68 MAGNESIUM Omeprazole (as magnesium) Omeprazole magnesium Omeprazole magnesium salt Prilosec Prilosec otc
Status
Molecule Category	Salt-form
UNII	426QFE7XLK

Structure


InChI Key	KWORUUGOSLYAGD-UHFFFAOYSA-N
Smiles	COc1ccc2[n-]c([S+]([O-])Cc3ncc(C)c(OC)c3C)nc2c1.COc1ccc2[n-]c([S+]([O-])Cc3ncc(C)c(OC)c3C)nc2c1.[Mg+2]
InChI	InChI=1S/2C17H18N3O3S.Mg/c21-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h25-8H,9H2,1-4H3;/q2*-1;+2

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C34H36MgN6O6S2
Molecular Weight	713.14
AlogP	2.9
Hydrogen Bond Acceptor	5.0
Hydrogen Bond Donor	1.0
Number of Rotational Bond	5.0
Polar Surface Area	77.1
Molecular species	NEUTRAL
Aromatic Rings	3.0
Heavy Atoms	24.0

Pharmacology

Mechanism of Action	Action	Reference
Potassium-transporting ATPase inhibitor	INHIBITOR	FDA PubMed PubMed PubMed

Target Conservation


Protein: Potassium-transporting ATPase Description: Potassium-transporting ATPase alpha chain 1 Organism : Homo sapiens P20648 ENSG00000105675











Protein: Potassium-transporting ATPase Description: Potassium-transporting ATPase subunit beta Organism : Homo sapiens P51164 ENSG00000186009

Cross References

Resources	Reference
ChEBI	94401
ChEMBL	CHEMBL1567328
FDA SRS	426QFE7XLK
SureChEMBL	SCHEMBL722792

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025