EcoDrugPlus


Synonyms	GS-0938 GS0938 Gs-0938 PSI-938 PSI352938 PSI938 Psi-352938
Status
Molecule Category	Free-form
UNII	3Z30JH9QX1

Synonyms

GS-0938

GS0938

Gs-0938

PSI-938

PSI352938

PSI938

Psi-352938

Status

Molecule Category

Free-form

UNII

3Z30JH9QX1


InChI Key	PVRFQJIRERYGTQ-UYISCHNFSA-N
Smiles	CCOc1nc(N)nc2c1ncn2[C@@H]1O[C@@H]2COP(=O)(OC(C)C)O[C@H]2[C@@]1(C)F
InChI	InChI=1S/C16H23FN5O6P/c1-5-24-13-10-12(20-15(18)21-13)22(7-19-10)14-16(4,17)11-9(26-14)6-25-29(23,28-11)27-8(2)3/h7-9,11,14H,5-6H2,1-4H3,(H2,18,20,21)/t9-,11-,14-,16-,29?/m1/s1

InChI Key

PVRFQJIRERYGTQ-UYISCHNFSA-N

Smiles

CCOc1nc(N)nc2c1ncn2[C@@H]1O[C@@H]2COP(=O)(OC(C)C)O[C@H]2[C@@]1(C)F

InChI

InChI=1S/C16H23FN5O6P/c1-5-24-13-10-12(20-15(18)21-13)22(7-19-10)14-16(4,17)11-9(26-14)6-25-29(23,28-11)27-8(2)3/h7-9,11,14H,5-6H2,1-4H3,(H2,18,20,21)/t9-,11-,14-,16-,29?/m1/s1

Property Name	Value
Molecular Formula	C16H23FN5O6P
Molecular Weight	431.36
AlogP	2.38
Hydrogen Bond Acceptor	11.0
Hydrogen Bond Donor	1.0
Number of Rotational Bond	5.0
Polar Surface Area	132.84
Molecular species	NEUTRAL
Aromatic Rings	2.0
Heavy Atoms	29.0

Property Name

Value

Molecular Formula

C16H23FN5O6P

Molecular Weight

431.36

AlogP

2.38

Hydrogen Bond Acceptor

11.0

Hydrogen Bond Donor

1.0

Number of Rotational Bond

5.0

Polar Surface Area

132.84

Molecular species

NEUTRAL

Aromatic Rings

2.0

Heavy Atoms

29.0

Mechanism of Action	Action	Reference
Hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor	INHIBITOR	PubMed

Mechanism of Action

Action

Reference

Hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor

INHIBITOR

PubMed

Resources	Reference
ChEMBL	CHEMBL2160007
FDA SRS	3Z30JH9QX1
SureChEMBL	SCHEMBL2679397

Resources

Reference

ChEMBL

CHEMBL2160007

FDA SRS

3Z30JH9QX1

SureChEMBL

SCHEMBL2679397

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

PSI-352938

Structure

Physicochemical Descriptors

Pharmacology

Cross References