MOEXIPRIL HYDROCHLORIDE

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Search structure


Synonyms	CI 925 CI-925 Moexipril hcl Moexipril hydrochloride Perdix RS-10085-197 SPM 925 SPM-925 Univasc
Status
Molecule Category	Salt-form
UNII	Q1UMG3UH45
EPA CompTox	DTXSID7044267

Structure


InChI Key	JXRAXHBVZQZSIC-JKVLGAQCSA-N
Smiles	CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1Cc2cc(OC)c(OC)cc2C[C@H]1C(=O)O.Cl
InChI	InChI=1S/C27H34N2O7.ClH/c1-5-36-27(33)21(12-11-18-9-7-6-8-10-18)28-17(2)25(30)29-16-20-15-24(35-4)23(34-3)14-19(20)13-22(29)26(31)32;/h6-10,14-15,17,21-22,28H,5,11-13,16H2,1-4H3,(H,31,32);1H/t17-,21-,22-;/m0./s1

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C27H35ClN2O7
Molecular Weight	535.04
AlogP	2.58
Hydrogen Bond Acceptor	7.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	11.0
Polar Surface Area	114.4
Molecular species	ACID
Aromatic Rings	2.0
Heavy Atoms	36.0

Pharmacology

Mechanism of Action	Action	Reference
Angiotensin-converting enzyme inhibitor	INHIBITOR	DailyMed

Target Conservation


Protein: Angiotensin-converting enzyme Description: Angiotensin-converting enzyme Organism : Homo sapiens P12821 ENSG00000159640

Cross References

Resources	Reference
ChEBI	6961
ChEMBL	CHEMBL1200534
FDA SRS	Q1UMG3UH45
SureChEMBL	SCHEMBL40877

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025