EcoDrugPlus


Synonyms	Anavex Anavex 2-73 Blarcamesine
Status
Molecule Category	Free-form
UNII	9T210MMZ3F
EPA CompTox	DTXSID60941344

Synonyms

Anavex

Anavex 2-73

Blarcamesine

Status

Molecule Category

Free-form

UNII

9T210MMZ3F

EPA CompTox

DTXSID60941344


InChI Key	BOTHKNZTGGXFEQ-UHFFFAOYSA-N
Smiles	CN(C)CC1CCOC1(c1ccccc1)c1ccccc1
InChI	InChI=1S/C19H23NO/c1-20(2)15-18-13-14-21-19(18,16-9-5-3-6-10-16)17-11-7-4-8-12-17/h3-12,18H,13-15H2,1-2H3

InChI Key

BOTHKNZTGGXFEQ-UHFFFAOYSA-N

Smiles

CN(C)CC1CCOC1(c1ccccc1)c1ccccc1

InChI

InChI=1S/C19H23NO/c1-20(2)15-18-13-14-21-19(18,16-9-5-3-6-10-16)17-11-7-4-8-12-17/h3-12,18H,13-15H2,1-2H3

Property Name	Value
Molecular Formula	C19H23NO
Molecular Weight	281.4
AlogP	3.53
Hydrogen Bond Acceptor	2.0
Number of Rotational Bond	4.0
Polar Surface Area	12.47
Molecular species	BASE
Aromatic Rings	2.0
Heavy Atoms	21.0

Property Name

Value

Molecular Formula

C19H23NO

Molecular Weight

281.4

AlogP

3.53

Hydrogen Bond Acceptor

2.0

Number of Rotational Bond

4.0

Polar Surface Area

12.47

Molecular species

BASE

Aromatic Rings

2.0

Heavy Atoms

21.0

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Membrane receptor	-	860	-	-	-

Targets

EC50(nM)

IC50(nM)

Kd(nM)

Ki(nM)

Inhibition(%)

Membrane receptor

860

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Homo sapiens	-	860	-	-	-

EC50(nM)

IC50(nM)

Kd(nM)

Ki(nM)

Inhibition(%)

Homo sapiens

860

Resources	Reference
CAS NUMBER	195615-83-9
ChEMBL	CHEMBL4297224
DrugBank	DB05592
FDA SRS	9T210MMZ3F
SureChEMBL	SCHEMBL181634

Resources

Reference

CAS NUMBER

ChEMBL

DrugBank

FDA SRS

SureChEMBL

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, Volume 54, Issue D1, 6 January 2026, Pages D1397–D1404, https://doi.org/10.1093/nar/gkaf1251

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 23^rd March 2026

BLARCAMESINE

Structure

Physicochemical Descriptors

Pharmacology

Cross References