EcoDrugPlus


Synonyms	AZD8418 Azd 8418 Azd-8418 Azd8418
Status
Molecule Category	Free-form
UNII	7U6B825568

Synonyms

AZD8418

Azd 8418

Azd-8418

Azd8418

Status

Molecule Category

Free-form

UNII

7U6B825568


InChI Key	MCPBSUCAISQZQK-JTQLQIEISA-N
Smiles	C[C@@H](C1CC1)N1Cc2cc(-c3cc(C(=O)N(C)C)no3)cc(Cl)c2C1=O
InChI	InChI=1S/C19H20ClN3O3/c1-10(11-4-5-11)23-9-13-6-12(7-14(20)17(13)19(23)25)16-8-15(21-26-16)18(24)22(2)3/h6-8,10-11H,4-5,9H2,1-3H3/t10-/m0/s1

InChI Key

MCPBSUCAISQZQK-JTQLQIEISA-N

Smiles

C[C@@H](C1CC1)N1Cc2cc(-c3cc(C(=O)N(C)C)no3)cc(Cl)c2C1=O

InChI

InChI=1S/C19H20ClN3O3/c1-10(11-4-5-11)23-9-13-6-12(7-14(20)17(13)19(23)25)16-8-15(21-26-16)18(24)22(2)3/h6-8,10-11H,4-5,9H2,1-3H3/t10-/m0/s1

Property Name	Value
Molecular Formula	C19H20ClN3O3
Molecular Weight	373.84
AlogP	3.45
Hydrogen Bond Acceptor	4.0
Number of Rotational Bond	4.0
Polar Surface Area	66.65
Molecular species	NEUTRAL
Aromatic Rings	2.0
Heavy Atoms	26.0

Property Name

Value

Molecular Formula

C19H20ClN3O3

Molecular Weight

373.84

AlogP

3.45

Hydrogen Bond Acceptor

4.0

Number of Rotational Bond

4.0

Polar Surface Area

66.65

Molecular species

NEUTRAL

Aromatic Rings

2.0

Heavy Atoms

26.0

Resources	Reference
ChEMBL	CHEMBL4297355
DrugBank	DB13102
FDA SRS	7U6B825568
SureChEMBL	SCHEMBL1178353

Resources

Reference

ChEMBL

DrugBank

FDA SRS

SureChEMBL

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

AZD-8418

Structure

Physicochemical Descriptors

Cross References