| Synonyms | |
| Status | |
| Molecule Category | UNKNOWN |
| ATC | R02AA03 |
| UNII | 1NKX3648J9 |
| EPA CompTox | DTXSID9041362 |
Structure
| InChI Key | DBHODFSFBXJZNY-UHFFFAOYSA-N |
|---|---|
| Smiles | |
| InChI |
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Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C7H6Cl2O |
| Molecular Weight | 177.03 |
| AlogP | 2.49 |
| Hydrogen Bond Acceptor | 1.0 |
| Hydrogen Bond Donor | 1.0 |
| Number of Rotational Bond | 1.0 |
| Polar Surface Area | 20.23 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 1.0 |
| Heavy Atoms | 10.0 |
Bioactivity
| Mechanism of Action | Action | Reference |
|---|---|---|
| Sodium channel alpha subunit blocker | BLOCKER | PubMed PubMed PubMed PubMed PubMed |
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Protein: Sodium channel alpha subunit Description: Sodium channel protein type 1 subunit alpha Organism : Homo sapiens P35498 ENSG00000144285 |
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Protein: Sodium channel alpha subunit Description: Sodium channel protein type 4 subunit alpha Organism : Homo sapiens P35499 ENSG00000007314 |
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Protein: Sodium channel alpha subunit Description: Sodium channel protein type 5 subunit alpha Organism : Homo sapiens Q14524 ENSG00000183873 |
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Protein: Sodium channel alpha subunit Description: Sodium channel protein type 9 subunit alpha Organism : Homo sapiens Q15858 ENSG00000169432 |
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Protein: Sodium channel alpha subunit Description: Sodium channel protein type 2 subunit alpha Organism : Homo sapiens Q99250 ENSG00000136531 |
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Protein: Sodium channel alpha subunit Description: Sodium channel protein type 3 subunit alpha Organism : Homo sapiens Q9NY46 ENSG00000153253 |
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Protein: Sodium channel alpha subunit Description: Sodium channel protein type 11 subunit alpha Organism : Homo sapiens Q9UI33 ENSG00000168356 |
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Protein: Sodium channel alpha subunit Description: Sodium channel protein type 8 subunit alpha Organism : Homo sapiens Q9UQD0 ENSG00000196876 |
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Protein: Sodium channel alpha subunit Description: Sodium channel protein type 10 subunit alpha Organism : Homo sapiens Q9Y5Y9 ENSG00000185313 |
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Cross References
| Resources | Reference |
|---|---|
| ChEBI | 48220 |
| ChEMBL | CHEMBL3184437 |
| DrugBank | DB13269 |
| DrugCentral | 3140 |
| FDA SRS | 1NKX3648J9 |
| PubChem | 15684 |
| SureChEMBL | SCHEMBL41323 |
| ZINC | ZINC000000157458 |
CONTENTS