MIVAVOTINIB CITRATE

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Synonyms
Status
Molecule Category Salt-form
UNII 6ZJ8V3Q0H1

Structure

InChI Key ZVPYVZMKBQYKQG-ZVWHLABXSA-N
Smiles Cn1cc(-c2nc(N[C@@H]3CCCC[C@@H]3N)c(F)c3c2C(=O)NC3)cn1.O=C(O)CC(O)(CC(=O)O)C(=O)O
InChI
InChI=1S/C17H21FN6O.C6H8O7/c1-24-8-9(6-21-24)15-13-10(7-20-17(13)25)14(18)16(23-15)22-12-5-3-2-4-11(12)19;7-3(8)1-6(13,5(11)12)2-4(9)10/h6,8,11-12H,2-5,7,19H2,1H3,(H,20,25)(H,22,23);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/t11-,12+;/m0./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C23H29FN6O8
Molecular Weight 536.52
AlogP 1.55
Hydrogen Bond Acceptor 6.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 3.0
Polar Surface Area 97.86
Molecular species BASE
Aromatic Rings 2.0
Heavy Atoms 25.0

Pharmacology

Mechanism of Action Action Reference
Tyrosine-protein kinase SYK inhibitor INHIBITOR Other Other

Target Conservation

Protein: Tyrosine-protein kinase SYK
Description: Tyrosine-protein kinase SYK
Organism : Homo sapiens
P43405 ENSG00000165025

Cross References

Resources Reference
ChEMBL CHEMBL4594253
FDA SRS 6ZJ8V3Q0H1
PubChem 118980937
SureChEMBL SCHEMBL17632419
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