DUVOGLUSTAT HYDROCHLORIDE

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Synonyms
Status
Molecule Category Salt-form
UNII 0RN23C42QR

Structure

InChI Key ZJIHMALTJRDNQI-VFQQELCFSA-N
Smiles Cl.OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O
InChI
InChI=1S/C6H13NO4.ClH/c8-2-3-5(10)6(11)4(9)1-7-3;/h3-11H,1-2H2;1H/t3-,4+,5-,6-;/m1./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C6H14ClNO4
Molecular Weight 199.63
AlogP -2.97
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 5.0
Number of Rotational Bond 1.0
Polar Surface Area 92.95
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 11.0

Pharmacology

Mechanism of Action Action Reference
Lysosomal alpha-glucosidase stabiliser STABILISER PubMed
EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Homo sapiens
- 70 - - -

Target Conservation

Protein: Lysosomal alpha-glucosidase
Description: Lysosomal alpha-glucosidase
Organism : Homo sapiens
P10253 ENSG00000171298

Cross References

Resources Reference
ChEMBL CHEMBL460785
FDA SRS 0RN23C42QR
PubChem 13018787
SureChEMBL SCHEMBL1320203
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