IRX-4204


InChI Key	BOOOLEGQBVUTKC-NVQSDHBMSA-N
Smiles	CC(/C=C/[C@@H]1C[C@]1(C)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C\C(=O)O
InChI	InChI=1S/C24H32O2/c1-16(13-21(25)26)7-8-18-15-24(18,6)17-9-10-19-20(14-17)23(4,5)12-11-22(19,2)3/h7-10,13-14,18H,11-12,15H2,1-6H3,(H,25,26)/b8-7+,16-13+/t18-,24-/m1/s1

Mechanism of Action	Action	Reference
Retinoid X receptor agonist	AGONIST	PubMed Other Other

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Transcription factor Nuclear receptor Nuclear hormone receptor subfamily 1 Nuclear hormone receptor subfamily 1 group C Nuclear hormone receptor subfamily 1 group C member 3	8.6-54	-	-	-	-
Transcription factor Nuclear receptor Nuclear hormone receptor subfamily 2 Nuclear hormone receptor subfamily 2 group B Nuclear hormone receptor subfamily 2 group B member 1	0.2	6	0.4-0.4	-	-
Transcription factor Nuclear receptor Nuclear hormone receptor subfamily 2 Nuclear hormone receptor subfamily 2 group B Nuclear hormone receptor subfamily 2 group B member 2	0.8	-	3.6	-	-
Transcription factor Nuclear receptor Nuclear hormone receptor subfamily 2 Nuclear hormone receptor subfamily 2 group B Nuclear hormone receptor subfamily 2 group B member 3	0.08	-	3.8	-	-

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Cercopithecidae	-	6	-	-	-
Homo sapiens	-	-	0.4	-	-


Protein: Retinoid X receptor Description: Retinoic acid receptor RXR-alpha Organism : Homo sapiens P19793 ENSG00000186350











Protein: Retinoid X receptor Description: Retinoic acid receptor RXR-beta Organism : Homo sapiens P28702 ENSG00000204231











Protein: Retinoid X receptor Description: Retinoic acid receptor RXR-gamma Organism : Homo sapiens P48443 ENSG00000143171

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