TIAPRIDE HYDROCHLORIDE

/static/temp/default.svg

Search structure


Synonyms	Gramalil Italprid Luxoben Sereprile Tiapridal Tiapride hcl Tiapride hydrochloride Tiapridex
Status
Molecule Category	Salt-form
UNII	25N106WEDO
EPA CompTox	DTXSID4045210

Structure


InChI Key	OTFDPNXIVHBTKW-UHFFFAOYSA-N
Smiles	CCN(CC)CCNC(=O)c1cc(S(C)(=O)=O)ccc1OC.Cl
InChI	InChI=1S/C15H24N2O4S.ClH/c1-5-17(6-2)10-9-16-15(18)13-11-12(22(4,19)20)7-8-14(13)21-3;/h7-8,11H,5-6,9-10H2,1-4H3,(H,16,18);1H

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C15H25ClN2O4S
Molecular Weight	364.9
AlogP	1.17
Hydrogen Bond Acceptor	5.0
Hydrogen Bond Donor	1.0
Number of Rotational Bond	8.0
Polar Surface Area	75.71
Molecular species	NEUTRAL
Aromatic Rings	1.0
Heavy Atoms	22.0

Pharmacology

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides	-	-	-	-	94.93-106.24

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Cricetulus griseus	-	-	-	-	94.93-106.24

Cross References

Resources	Reference
ChEBI	32220
ChEMBL	CHEMBL1256772
FDA SRS	25N106WEDO
PubChem	39855
SureChEMBL	SCHEMBL355315

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025