SELURAMPANEL

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Synonyms
Status
Molecule Category Free-form
UNII 7WG1MR7DAR
EPA CompTox DTXSID00238467

Structure

InChI Key MCECSFFXUPEPDB-UHFFFAOYSA-N
Smiles CC(C)c1cc2[nH]c(=O)n(NS(C)(=O)=O)c(=O)c2cc1-c1ccnn1C
InChI
InChI=1S/C16H19N5O4S/c1-9(2)10-8-13-12(7-11(10)14-5-6-17-20(14)3)15(22)21(16(23)18-13)19-26(4,24)25/h5-9,19H,1-4H3,(H,18,23)

Physicochemical Descriptors

Property Name Value
Molecular Formula C16H19N5O4S
Molecular Weight 377.43
AlogP 0.72
Hydrogen Bond Acceptor 7.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 4.0
Polar Surface Area 118.85
Molecular species NEUTRAL
Aromatic Rings 3.0
Heavy Atoms 26.0

Pharmacology

Mechanism of Action Action Reference
Glutamate receptor ionotropic AMPA antagonist ANTAGONIST PubMed Wikipedia

Target Conservation

Protein: Glutamate receptor ionotropic kainate
Description: Glutamate receptor ionotropic, kainate 1
Organism : Homo sapiens
P39086 ENSG00000171189
Protein: Glutamate receptor ionotropic AMPA
Description: Glutamate receptor 1
Organism : Homo sapiens
P42261 ENSG00000155511
Protein: Glutamate receptor ionotropic AMPA
Description: Glutamate receptor 2
Organism : Homo sapiens
P42262 ENSG00000120251
Protein: Glutamate receptor ionotropic AMPA
Description: Glutamate receptor 3
Organism : Homo sapiens
P42263 ENSG00000125675
Protein: Glutamate receptor ionotropic AMPA
Description: Glutamate receptor 4
Organism : Homo sapiens
P48058 ENSG00000152578
Protein: Glutamate receptor ionotropic kainate
Description: Glutamate receptor ionotropic, kainate 2
Organism : Homo sapiens
Q13002 ENSG00000164418
Protein: Glutamate receptor ionotropic kainate
Description: Glutamate receptor ionotropic, kainate 3
Organism : Homo sapiens
Q13003 ENSG00000163873
Protein: Glutamate receptor ionotropic kainate
Description: Glutamate receptor ionotropic, kainate 4
Organism : Homo sapiens
Q16099 ENSG00000149403
Protein: Glutamate receptor ionotropic kainate
Description: Glutamate receptor ionotropic, kainate 5
Organism : Homo sapiens
Q16478 ENSG00000105737

Cross References

Resources Reference
ChEMBL CHEMBL3545042
DrugBank DB12367
FDA SRS 7WG1MR7DAR
PubChem 45381907
SureChEMBL SCHEMBL1660562
ZINC ZINC000116796247
CONTENTS