LYSERGIDE

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Synonyms
LSD
Status
Molecule Category Free-form
UNII 8NA5SWF92O
EPA CompTox DTXSID1023231

Structure

InChI Key VAYOSLLFUXYJDT-RDTXWAMCSA-N
Smiles CCN(CC)C(=O)[C@@H]1C=C2c3cccc4[nH]cc(c34)C[C@H]2N(C)C1
InChI
InChI=1S/C20H25N3O/c1-4-23(5-2)20(24)14-9-16-15-7-6-8-17-19(15)13(11-21-17)10-18(16)22(3)12-14/h6-9,11,14,18,21H,4-5,10,12H2,1-3H3/t14-,18-/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C20H25N3O
Molecular Weight 323.44
AlogP 2.91
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 3.0
Polar Surface Area 39.34
Molecular species NEUTRAL
Aromatic Rings 2.0
Heavy Atoms 24.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Adrenergic receptor
- - - 140-740 -
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Dopamine receptor
- - - 27-340 -
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Serotonin receptor
9.8-9.8 - - 1.1-93 -
EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Homo sapiens
- - - 2.6-4 -
Rattus norvegicus
9.8 - - 3.5-5.5 -

Related Entries

Cross References

Resources Reference
ChEBI 6605
ChEMBL CHEMBL263881
DrugBank DB04829
DrugCentral 1621
FDA SRS 8NA5SWF92O
Guide to Pharmacology 17
KEGG C07542
PDB 7LD
PubChem 5761
SureChEMBL SCHEMBL113755
ZINC ZINC000096903803
CONTENTS