NEBOGLAMINE

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Synonyms
Status
Molecule Category Free-form
UNII 12EA34U5B8
EPA CompTox DTXSID2045787

Structure

InChI Key VCRGLZYPNNAVRP-JTQLQIEISA-N
Smiles CC1(C)CCC(NC(=O)[C@@H](N)CCC(=O)O)CC1
InChI
InChI=1S/C13H24N2O3/c1-13(2)7-5-9(6-8-13)15-12(18)10(14)3-4-11(16)17/h9-10H,3-8,14H2,1-2H3,(H,15,18)(H,16,17)/t10-/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C13H24N2O3
Molecular Weight 256.35
AlogP 1.26
Hydrogen Bond Acceptor 3.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 5.0
Polar Surface Area 92.42
Molecular species ACID
Aromatic Rings 0.0
Heavy Atoms 18.0

Pharmacology

Mechanism of Action Action Reference
Glutamate [NMDA] receptor positive allosteric modulator POSITIVE ALLOSTERIC MODULATOR PubMed PubMed Wikipedia

Target Conservation

Protein: Glutamate [NMDA] receptor
Description: Glutamate receptor ionotropic, NMDA 2D
Organism : Homo sapiens
O15399 ENSG00000105464
Protein: Glutamate [NMDA] receptor
Description: Glutamate receptor ionotropic, NMDA 3B
Organism : Homo sapiens
O60391 ENSG00000116032
Protein: Glutamate [NMDA] receptor
Description: Glutamate receptor ionotropic, NMDA 1
Organism : Homo sapiens
Q05586 ENSG00000176884
Protein: Glutamate [NMDA] receptor
Description: Glutamate receptor ionotropic, NMDA 2A
Organism : Homo sapiens
Q12879 ENSG00000183454
Protein: Glutamate [NMDA] receptor
Description: Glutamate receptor ionotropic, NMDA 2B
Organism : Homo sapiens
Q13224 ENSG00000273079
Protein: Glutamate [NMDA] receptor
Description: Glutamate receptor ionotropic, NMDA 2C
Organism : Homo sapiens
Q14957 ENSG00000161509
Protein: Glutamate [NMDA] receptor
Description: Glutamate receptor ionotropic, NMDA 3A
Organism : Homo sapiens
Q8TCU5 ENSG00000198785

Cross References

Resources Reference
ChEMBL CHEMBL1255840
FDA SRS 12EA34U5B8
PubChem 3074827
SureChEMBL SCHEMBL1353060
ZINC ZINC000000006138
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