EcoDrugPlus


Synonyms	Cyclizine hcl Cyclizine hydrochloride Marzine NSC-169102
Status
Molecule Category	Salt-form
UNII	W0O1NHP4WE

Synonyms

Cyclizine hcl

Cyclizine hydrochloride

Marzine

NSC-169102

Status

Molecule Category

Salt-form

UNII

W0O1NHP4WE


InChI Key	UKPBEPCQTDRZSE-UHFFFAOYSA-N
Smiles	CN1CCN(C(c2ccccc2)c2ccccc2)CC1.Cl
InChI	InChI=1S/C18H22N2.ClH/c1-19-12-14-20(15-13-19)18(16-8-4-2-5-9-16)17-10-6-3-7-11-17;/h2-11,18H,12-15H2,1H3;1H

InChI Key

UKPBEPCQTDRZSE-UHFFFAOYSA-N

Smiles

CN1CCN(C(c2ccccc2)c2ccccc2)CC1.Cl

InChI

InChI=1S/C18H22N2.ClH/c1-19-12-14-20(15-13-19)18(16-8-4-2-5-9-16)17-10-6-3-7-11-17;/h2-11,18H,12-15H2,1H3;1H

Property Name	Value
Molecular Formula	C18H23ClN2
Molecular Weight	302.85
AlogP	3.02
Hydrogen Bond Acceptor	2.0
Number of Rotational Bond	3.0
Polar Surface Area	6.48
Molecular species	NEUTRAL
Aromatic Rings	2.0
Heavy Atoms	20.0

Property Name

Value

Molecular Formula

C18H23ClN2

Molecular Weight

302.85

AlogP

3.02

Hydrogen Bond Acceptor

2.0

Number of Rotational Bond

3.0

Polar Surface Area

6.48

Molecular species

NEUTRAL

Aromatic Rings

2.0

Heavy Atoms

20.0

Resources	Reference
ChEBI	51045
ChEMBL	CHEMBL1324714
FDA SRS	W0O1NHP4WE
PubChem	6420019
SureChEMBL	SCHEMBL97825

Resources

Reference

ChEBI

ChEMBL

FDA SRS

PubChem

SureChEMBL

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025

CYCLIZINE HYDROCHLORIDE

Structure

Physicochemical Descriptors

Cross References