STANOLONE


Synonyms	4-dihydrotestosterone 5alpha-dihydrotestosterone Anabolex Andractim Androstanolone Dihydrotestosterone Dihydrotestosterone (dht) NSC-10972 Neodrol Stanolone
Status
Molecule Category	Free-form
UNII	08J2K08A3Y
EPA CompTox	DTXSID9022364


InChI Key	NVKAWKQGWWIWPM-ABEVXSGRSA-N
Smiles	C[C@]12CCC(=O)C[C@@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](O)CC[C@@H]12
InChI	InChI=1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14-,15-,16-,17-,18-,19-/m0/s1

Property Name	Value
Molecular Formula	C19H30O2
Molecular Weight	290.45
AlogP	3.96
Hydrogen Bond Acceptor	2.0
Hydrogen Bond Donor	1.0
Polar Surface Area	37.3
Molecular species	NEUTRAL
Aromatic Rings	0.0
Heavy Atoms	21.0

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Enzyme Cytochrome P450 Cytochrome P450 family 19 Cytochrome P450 family 19A Cytochrome P450 19A1	-	-	-	220	-
Enzyme Oxidoreductase	-	-	-	-	49.6
Secreted protein	-	3.8-23	0.182	-	-
Transcription factor Nuclear receptor Nuclear hormone receptor subfamily 3 Nuclear hormone receptor subfamily 3 group C Nuclear hormone receptor subfamily 3 group C member 1	-	540	-	-	-
Transcription factor Nuclear receptor Nuclear hormone receptor subfamily 3 Nuclear hormone receptor subfamily 3 group C Nuclear hormone receptor subfamily 3 group C member 2	-	360	-	-	-
Transcription factor Nuclear receptor Nuclear hormone receptor subfamily 3 Nuclear hormone receptor subfamily 3 group C Nuclear hormone receptor subfamily 3 group C member 3	-	440-440	-	-	-
Transcription factor Nuclear receptor Nuclear hormone receptor subfamily 3 Nuclear hormone receptor subfamily 3 group C Nuclear hormone receptor subfamily 3 group C member 4	0.05-20	0-18.5	-	0.2-10	-

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Homo sapiens	0.13-15	0-540	0.182	0.2-220	49.6
Mus musculus	1.259-3.981	1	-	-	-
Oryctolagus cuniculus	-	440-440	-	-	-
Rattus norvegicus	0.97-2.8	1-23	-	0.27-0.69	-

Header

Compound Name

Maximum Phase

Compound Structure

Smile

Inchi

InchiKey

Compound Properties

Molecular Formula

Molecular Weight

ALogP

PSA

Resources	Reference
ChEBI	16330
ChEMBL	CHEMBL27769
DrugBank	DB02901
DrugCentral	3927
FDA SRS	08J2K08A3Y
Human Metabolome Database	HMDB0002961
Guide to Pharmacology	3455
KEGG	C03917
PDB	DHT
SureChEMBL	SCHEMBL15163
ZINC	ZINC000003814360

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025

STANOLONE

Structure

Physicochemical Descriptors

Pharmacology

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