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Cytochrome P450
Homo sapiens »
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IRINOTECAN SUCROSOFATE
Search structure
Synonyms
Irinotecan sucrosofate
MM-398
PEP-02
Status
Phase 3
Molecule Category
Free-form
UNII
OL741S3N8B
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Threshold (%) >=
70
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Action
Reference
DNA topoisomerase I inhibitor
INHIBITOR
PubMed
PubMed
Target Conservation
Protein: DNA topoisomerase I
Description: DNA topoisomerase 1
Organism : Homo sapiens
P11387
ENSG00000198900
Afrotheria
×
Query Gene :
ENSG00000198900
Protein : DNA topoisomerase I
Description: DNA topoisomerase 1
Organism : Homo sapiens
×
Amphibians
×
Query Gene :
ENSG00000198900
Protein : DNA topoisomerase I
Description: DNA topoisomerase 1
Organism : Homo sapiens
×
Birds
×
Query Gene :
ENSG00000198900
Protein : DNA topoisomerase I
Description: DNA topoisomerase 1
Organism : Homo sapiens
×
Early Vertebrates
Query Gene :
ENSG00000198900
Protein : DNA topoisomerase I
Description: DNA topoisomerase 1
Organism : Homo sapiens
×
Fish
×
Query Gene :
ENSG00000198900
Protein : DNA topoisomerase I
Description: DNA topoisomerase 1
Organism : Homo sapiens
×
Laurasiatheria
×
Query Gene :
ENSG00000198900
Protein : DNA topoisomerase I
Description: DNA topoisomerase 1
Organism : Homo sapiens
×
Marsupials and Monotremes
×
Query Gene :
ENSG00000198900
Protein : DNA topoisomerase I
Description: DNA topoisomerase 1
Organism : Homo sapiens
×
Other Euarchontoglires
×
Query Gene :
ENSG00000198900
Protein : DNA topoisomerase I
Description: DNA topoisomerase 1
Organism : Homo sapiens
×
Other chordates
×
Query Gene :
ENSG00000198900
Protein : DNA topoisomerase I
Description: DNA topoisomerase 1
Organism : Homo sapiens
×
Primates
×
Query Gene :
ENSG00000198900
Protein : DNA topoisomerase I
Description: DNA topoisomerase 1
Organism : Homo sapiens
×
Reptiles
×
Query Gene :
ENSG00000198900
Protein : DNA topoisomerase I
Description: DNA topoisomerase 1
Organism : Homo sapiens
×
Xenarthra
×
Query Gene :
ENSG00000198900
Protein : DNA topoisomerase I
Description: DNA topoisomerase 1
Organism : Homo sapiens
×
Query Gene :
ENSG00000198900
Target Name : DNA topoisomerase I
Organism : Homo sapiens
Cross References
Resources
Reference
CAS NUMBER
1361317-83-0
ChEMBL
CHEMBL3039564
FDA SRS
OL741S3N8B
PubChem
76964235
CONTENTS
Structure
Pharmacology
Target Conservation